180 results
The objective of this study is to support the pharma partner*s Phase III trial using Tina-quant Lipoprotein (a) RxDx assay for subject selection and optional batch testing of follow-up samples. This study is carried out to evaluate the performance…
Primary Objective: Compare Atellica VTLi Sepsis biomarker values from capillary whole blood from fingerstick with anticoagulated whole blood and plasma from venipuncture.Secondary Objectives: Correlate the blood and plasma outcomes on the Atellica…
To compare the effects on glycemic control, patient reported outcomes (PRO) and experiences (PRE) of rt-CGM with FGM in a real-life outpatient setting among persons with T1D.
• The primary objective is to demonstrate non-inferiority of the detection rate of clinically significant prostate cancer (defined as GG >= 2) in targeted biopsies based on PCaVision imaging (PCaVision pathway) in comparison with the…
- special attention for the development and harmonization of the pre-analysis of liquid biopsy, for blood as well as urine, andnext to this for ctDNA- special attention for the detection of PIK3CA mutations in blood and urineSimultaneously also the…
To assess whether minimally invasive nonsurgical microwave ablation (MWA) followed by postprocedural MRI scan can be an alternative treatment for breast surgery in early stage breast cancer: a non-inferiority study .Is the quality of life, cosmetic…
The goals of our study are: 1) to evaluate the performance of a single hs-troponin measurement using universal and sex-specific cut-off values; 2) to evaluate whether embedding hs-troponin in a clinical risk score (HEART, INTERCHEST, Marburg Heart…
The primary aim of this study is early identification of sepsis (and septic shock) and cardiovascular instability, based on the hemodynamic profile of ED patients. Continuous noninvasive arterial pressure waveform signals will be collected with the…
To test if a CRT-targeted resuscitation based on clinical hemodynamic phenotyping can improve a hierarchical clinical outcome - mortality, time to cessation of vital organ support, and length of hospital stay, all within 28 days - in septic shock…
The aim of this project is to validate 3 novel biomarkers (FDG PET/CT, WES and NGF). The utilization goal is to implement these biomarkers afterwards in clinical practice to rationalize treatment strategies. The primary objective is to validate the…
Primary Objective: 1. To determine the feasibility and clinical relevance of quantifiable parameters from intraoperative ALFA-measurements. Secondary Objective(s): 1. Determine the intraoperative applicability of ALFA. 2. Determine the effect of…
To evaluate existing an currently practiced methods for assessing ocular surface characteristics of DED in order to evaluate their characteristics and comparability.
The main objective is to research the practicability of postoperative fLTB through the endotracheal tube, right before/during planned extubation in the intensive care unit (ICU) in newborn babies after EA correction.
Assessment and quantification of the function of the external anal sphincter by means of 4D ultrasound.
The purposes of this study are to uncover1. Which surgical methods are least likely to cause the CMS and if there is a difference in risk between primary surgery andreoperation2. Which patients may be genetically predisposed to developing the CMS 3…
Evaluation of the fractional uptake rate (FUR) in 18F-FDG PET/CT to assess tumour metabolic activity
Primary objective: To investigate whether FDG PET quantification using the FUR is superior compared to the clinically used SUV.Secondary objectives: 1) To evaluate whether the metabolic tumor activity Km can be accurately asessed with 18F-FDG PET…
Primary objectiveThe primary objectives of this feasibility clinical investigation are to assess the overall usability of the Philips AirWaze investigational device as measured by the System Usability Score (SUS), and the accuracy of the tool-in-…
Demonstrate the suitability of cardiorespiratory monitoring directly after birth using a novel, wireless, non-adhesive device.
The objectives of this multicenter performance evaluation study comprise an assessment of the analytical performance, the reliability and robustness of the system to obtain a CE mark.
1) To determine whether advanced MRI techniques can detect active inflammatory Gd enhancing lesions. 2) To determine whether blood biomarkers are associated with the presence of enhancing brain lesions in MS. 3) To determine whether advanced MRI…