4538 results
We hypothesize that CTC detection through diagnostic leukapheresis improves the detection rate among ER+, N+ primary breast cancer who have received 5 years of adjuvant endocrine therapy and will be a promising technique for risk classification in…
Vitamin C deficiency may play a role in the symptoms of patients with chronic kidney failure and eventually renal replacement therapy
The gaol of the present study is to determine the role of platelet derived TFPI on coagulation in healthy male subjects (n=10) and in healthy female subjects either using ( n=10) or not using oral contraceptives (n=10). Additionally 8 healthy…
The main objective of this pilot study is to evaluate the burden of an additional CTA and MRA procedure in patients, and to evaluate the quality of the CTA and MRA protocols.
Therefore, the aim of this study will be to assess reproducibility of pseudo-CASL (p-CASL) between 3.0 Tesla MR scanners of two vendors in two medical centers.
To assess the usefulness of NBI in the visualisation of PVs in Western BE patients (in this study using the new Excera III NBI-system), to investigate the discordance between the Japanese and Western definition of de distal end of the Barrett*s…
To measure changes in lymph nodes on 3D CUBE imaging during (chemo)radiotherapy of head and neck squamous cell carcinoma. By using serial imaging during treatment with a relatively short scan time, we want to establish a biological model of changes…
· Explore the relative impacts of iodine concentration versus iodine delivery rate on intra-coronary attenuation. · Describe the effect of iodine concentration on contrast bolus characteristics e.g. bolus homogeneity, time-to-peak, and pressure…
This study has three objectives:1. To describe flow patterns in the left atrium in patient with sinus rhythm and atrial fibrillation. 2. To prospectively verify the data in patients with atrial fibrillation3. Correlation of abnormal flow patterns to…
Determine the technical success, diagnostic accuracy, safety and quality of procedure (evaluated by the endoscopist) of the E.G.Scan* compared to conventional upper endoscopy in patients referred for diagnostic upper endoscopy.
Aim of this study is to confirm the results from ex vivo research in humans in a clinical setting. The objective is to perform optical spectroscopy measurements during surgical procedures in vivo, involving resection of either breast, liver or lung…
To monitor the electric activity of the urinary bladder, and to localize the pacemaker, and the path of electric signal propagation of the detrusor muscle contractions.
The present study is designed to validate the Dutch IIEF. The psychometric properties of the Dutch version of the IIEF will be investigated.
Primary objectives:• To demonstrate that low ratios of sFlt-1/PlGF predict absence of PE / eclampsia / HELLP (according to diagnostic criteria) within one week after start visit (= Visit 1).• To demonstrate that high ratios of sFlt-1/PlGF predict PE…
The aim of this study if PET using [18F] fluorothymidine (FLT), an imaging biomarker, performed at week 10 of concomitant radio/chemotherapy for patients with newly diagnosed GBM is superior to MRI at 10 weeks to evaluate treatment response and to…
The overall aim is to develop an objective symptom profile of non specific neckpain patients which addresses more facets of the health problem, including sensorimotor dysfunction. The first stage is the establishment of an objective quantification…
To assess in a pilot setting whether there are differences (including sensitivity and specificity) in pen motion, grip force patterns and muscle activity, derived using a newly developed system for handwriting monitoring, between A: patients with…
To determine whether the use of epinephrine saline irrigation in therapeutic shoulder arthroscopy with need for subacromial procedures should significantly increase clarity of the view.
The primary goal of this study is to develop a protocol for future studies in patients after a first seizure. We investigate 3 methodological aspects. - What is the effect on the auditory evoked potential of different types of noise masking?- What…
The objective of the study is to determine whether it is necessary to take the blood pressure lowering medication (β-blocker, ACE-inhibitors or diuretics) of a patient into account prior to blood sampling for pheochromocytoma diagnostics. Therefore…