296 results
To validate and compare smartphone-connected blood pressure monitors produced by Withings, Qardio and iHealth with the gold standard and a validated automatic blood pressure monitor.
We purpose to determine whether the international normative values are applicable in our center in 10 healthy participants. Furthermore, CCM will be introduced as additional diagnostic tool in patients with (possible) SFN.
To identify biomarkers associated with OSA in bariatric surgery patients prior to surgery; to investigate the effect of bariatric surgery on these with OSA associated biomarkers; to identify biomarkers that predict amelioration of OSA after…
The purpose of this study is to research the influence of vibration on the neck muscles on JPE and the effect of aging on this parameter in patients with a-specific neck pain. The second purpose is to research the influence of vibration on the neck…
To determine the efficacy of quantification of vitreous floaters captured by SLO-imaging technique for Nd:YAG vitreolysis for persisting vitreous floaters.
In the current study we aim to assess the energy requirements and physical activity patterns in professional soccer players along with their nutritional intake patterns. As such, this study will provide valuable information to optimize the…
Primary objective * To determine the maximum tolerated dose and recommended dose of metformin plus chloroquine in patients with IDH1/2MT glioma, IHCC and CS Secondary objectives * To describe the toxic effects of metformin plus chloroquine in…
To validate two novel genomic biomarkers that provide information with respect to the presence of PCa, disease aggressiveness, and progression towards recurrent and metastatic disease.
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
Identify DNA methylation markers suitable for sensitive and specific plasma-based detection of advanced colorectal adenomas.
The study is intended to (1) confirm the reduced x-ray shadow of the MicroTEE (S8-3t) probe, and to asses whether this results in a more delayed first pull back or a reduction in the number of pull backs or not; and (2) to evaluate the feasibility…
The key objective of this proposal is to develop a prediction tool, which will enable clinicians to detect an increased risk of developing chronic pain in JIA at an early stage of the disease. This tools consists of an assay for GRK2 expression.…
The primary objective is to investigate the influence of vigilance state on MEP amplitude in healthy adults. Secondary objectives are to develop a paradigm to stabilize vigilance state resulting in lower MEP amplitude variability in healthy adults…
The aim of this study is to test the feasibility of a GXTT, combined with a SET in adults with ID, through completion rate of the GXTT and the SET, the subjective experience of the participants and determining if the VO2peak of the SET is likely to…
High-field (7T) MRI and genetic biomarkers for neurocognitive impairment in type 2 diabetes melltius
The primary objectives: 1. To tailor and apply high-field multi-parametric and functional MRI techniques to identify cerebral biomarkers in DM2 and MetS patients compared to control subjects.2. To examine a specific set of genetic hypotheses in DM2…
Primary objectiveIs RRSO at age <= 45 in BRCA1/2 mutation carriers a risk factor for development of subclinical atherosclerosis, independent of traditional cardiovascular risk factors? Secondary objectiveAre menopausal symptoms in BRCA1/2…
Primary Objective: To study the options of the PulmoVista 500 system to visualize regional real-time lung ventilation in healthy volunteersResearch questions:- Can the PulmoVista 500 system provide sufficient information regarding regional lung…
The pilot study has three main objectives: 1) To determine the exposure to gluten in celiac patients on a gluten free diet and the variance within this exposure; 2) To determine the gluten content of gluten free- labelled products commonly used by…
Primary Objective: to determine the strength of the dynamic autoregulation of patients after cardiac arrest during the post cardiac arrest syndrome. Secondary Objectives:to observe the natural course of the autoregulation during the first year after…
We aim to investigate whether copeptin can be used as an early postoperative marker for development of DI. We will measure copeptin levels in patients just prior to and following transsphenoidal surgery to be able to investigate whether copeptin…