160 results
The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…
The main objective of the SOPI study is to select the HRD test that best predicts longest PFS on PARP-i in non-BRCA1/2 EOC patients, in order to adequately select patients that will benefit from a PARP-i. Secondary objectives are: to…
Primary Objective: To investigate which measures/definitions from continuous BP measurements (using Finapres) and from cerebral oxygenation measurements (using NIRS) are associated with associated with future fall incidents in older adults at risk…
To utilize the therascreen KRAS RGQ PCR Kit, as a screening test in Amgen*s Phase 3 Clinical Study Protocol 20210081, in order to identify patients with mCRC KRAS G12C mutation positive tumors to be enrolled in the drug clinical trial. Results of…
To compare the clinical value of MR quantitative parametric maps versus the use of GBCA MRI.
The objective of this study is to determine the ability of respiratory EMG measurements with a wearable to …
The objective is to improve the understanding of intracochlear electrocochleography for objective measurement of residual hearing. ECochG responses obtained postoperatively in patients with different aetiologies will be evaluated in…
Hand function impairment in systemic sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) study
Primary Objective: Determination of risk factors for hand function impairment in systemic sclerosis (SSc) patients with early disease, very early disease and established hand impairment (contractures) at 2 years follow-upSecondary Objective(s):-…
As verbs are better indicators of everyday language ability than nouns, the current project characterizes verb processing and verb learning abilities of children with PPFTs, and compares them to the abilities of typically developing children (aim 1…
The primary objective of the CRT-DRIVE study is to test the hypothesis that at least 75% of patients undergoing a CRT implantation guided by non-invasive electrical and venous anatomy assessment (XSPLINE technology) will show a reduction of left…
The primary objective is to investigate the feasibility of NIR fluorescence imaging with intra-arterial ICG to detect differences in foot perfusion following successful endovascular lower extremity revascularization.
To ascertain differences in mitochondrial and microcirculatory parameters between healthy older adults (> 65 years and ASA1-2) and more vulnerable elderly patients (> 65 years and ASA 3-4).
Our central hypothesis is that the RNA content of TEPs allows for the identification of glioblastoma progression, including the differentiation from pseudo-progression and radionecrosis. For this we plan to use two parallel approaches, i.e. the TEP-…
We aim to determine the added value of a direct FET-PET for clinical practice. The hypothesis is that the addition of FET-PET will lead to correct diagnosis more rapidly than regular MRI alone, and thus to a better quality of life for patients…
The aim of this study is to assess if ultrasonography of the ONSD can be used to safely rule out papilledema and to evaluate if ONSD measurement can replace funduscopy in the assessment of certain patients with suspected hypertensive emergency.
1.1 Primary Objectives1. To document the prevalence of ischemic intracoronary electrocardiogram changes in ANOCA patients with equivocal acetylcholine provocation test results.2. To document the diagnostic efficacy of the 12-lead Holter ECG to…
The main objective of the RE-SAMPLE VCP is to facilitate proactive disease management of COPD and CCCs. The study goal is to evaluate the feasibility of the VCP by assessing improvements in clinical outcomes, user acceptance, usability, and…
Several observational studies have been published evaluating DECTA for imaging of the lower legs, comparing this technique with conventional CTA. However, to the best of our knowledge, no randomised controlled trial has been conducted comparing both…
The primary objective is to demonstrate non-inferiority of the detection rate of clinically significant prostate cancer (defined as GG>=2) in targeted biopsies based on PGaVision imaging (PCaVision pathway) in comparison with the detection…