272 results
The main objective is to show whether imaging characteristics assessed at baseline can predict clinical events in patients with a 30-69 % symptomatic carotid stenosis.
Main questions:1. What is the success rate of antireflux surgery in children (reflux control) measured by means of validated and standardised investigation techniques?2. What is the effect of antireflux surgery on gastro-esophageal motility/function…
The purpose of this trial is to evaluate whether procalcitonin measurements are able to reduce antibiotic usage in Dutch intensive care units by reducing the duration of antibiotic treatment.
To discriminate the acquired anti-hormonal resistance phenotypes in patients based on ER expression levels by FES-PET in order to select patients eligible for estrogen therapy.
Our primary objective is to determine the incidence of EPS after kidney transplantation in patients previously treated by PD. We hypothesize that there is an increasing incidence of symptomatic and asymptomatic EPS after kidney transplantation.
The aim of this research is developing a non-invasive a method of early detection of CIS using scrotal ultrasound and semen diagnostic on CIS-cells. The results of this research will be used for the set-up of a screening study of CIS at men with an…
The objective of this study is threefold:1) compare the effectiveness and cost-effectiveness of brief CT added to maintenance AD versus maintenance AD alone versus guided tapering or discontinuation of AD with brief CT.2) examine whether the…
PrimaryTo investigate sensitivity and specificity of 3.0 Tesla MRI and MRS for dimension and composition assessment of carotid artery plaques, in particularly those plaques with lipid rich necrotic cores (LRNC), with the aim to develop these…
The primary objective of the study is to evaluate the feasibility of 89Zr-bevacizumab PET imaging as a biomarker before and during treatment with everolimus in patients with metastatic RCC. 89Zr-bevacizumab PET imaging will be regarded a promising…
- To investigate whether the effect of early-start rasagiline treatment (according to the ADAGIO study protocol) provided long term benefits over delayed-start.- To investigate the long-term effects of rasagiline in PD subjects who participated in…
To measure the differences of DCE MR images between patients with and without local recurrent prostate cancer in the follow up after primary treatment.
Primary objective:To compare the specificity of multiple voxel MR spectroscopy with MRI.Secondary objective: To decrease the number of false positive diagnostic outcomes by using multiple-voxel MR-spectroscopy and therefore to reduce benign biopsies…
To determine the accuracy of 18F-FAZA-PET/CT and OE-MRI scan in detecting hypoxic regions within the tumor using histological markers.
The focus of this study is to get more insight in the pathophysiology of IUGR. The main goal is to investigate the applicability of STIC in determining fetal cardiac function in IUGR.
Onset of effect of systemic therapy to enhance bone density (eg, bisphosphonates) is not immediate and may not adequately protect subjects with decreased bone density from fracture.Bisphosphonate therapy will typically require 2 to 3 years of active…
This study compares iMRI with cNN for the primary endpoint (percentage of residual tumor volume) and the secondary endpoints (complications, clinical functioning / quality of life, and survival).
Our overall aim is to create a cost effective non-invasive method of pre-surgical assessment of language and memory function using MEG scanning. We propose a research project with the key objective to evaluate the effectiveness of a Dutch…
Main objectiveTo describe the experienced pain sensations of temperature and to describe the different temperature sensitivity thresholds using Quantitative Sensory Test (QST) in the different patient groups.secondairy objectiveAs a measure of the…
Objective of the study is to asses quality of fracture reduction and patient-relevant outcomes with the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with traumatic intra-articular fractures of…
To investigate whether the extent of myocardial αvβ3 expression visualized by imaging with 99mTc -NC100692 Injection can be used as a surrogate endpoint for the outcome of therapeutic interventions, using standard and novel treatments (ACE-I vs. ACE…