23 results
This study aims to investigate the feasability to use DW-MRI for mediastinal restaging after concomitant chemoradiotherapy and the feasabilitiy to predict whether or not mediastinal downstaging will be achieved during concomitant chemoradiotherapy…
The proposed study aims to bring neuroimaging and genetics closer to the child/adolescent psychiatric clinic by developing automated classifiers, and obtain associated multimodal biomarker profiles. Such biomarkers are prospected to, aid in clinical…
Primary Objective: • To study the accuracy of a combined CT angiography and DECT for complete imaging of CAD compared to the reference standard, ICA and SPECT MPI. Secondary Objective(s): • To compare DECT analysis in the detection of perfusion…
Primary Objective: to determine the prevalence of MTWA in adults with congenital heart disease who are deemed to be at high risk for ventricular arrhythmias and sudden cardiac death.Secondary Objective(s): • to describe the clinical usefulness and…
A primary goal is to relate EEG based rsFC to changes in excitability of the brain. Since the excitability recorded with the MEPs reflect antiepileptic drug effects [1,2] it is assumed that these changes will be more pronounced after withdrawal of…
Determine if there is an age (young, middle age, old age) by condition (lying, standing) interaction in the neuronal excitability measured during the preparatory phase of an arm reaction task.
The primary objective of this study is to explore the PSA response rate to cabazitaxel in mCRPC patients who have progressed to docetaxel and to correlate the PSA response to AR-V7 expression in CTCs. Exploratory objectives include documenting the…
Using technology for improving diagnostics of non-specific lower back pain by physiotherapists
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to investigate the influence of induced changes to the healing…
Based on this background information and our preliminary data in this project we aim to perform longitudinal study in cystinosis patients to correlate clinical course under cysteamine therapy and 1) Markers of macrophage activation in patients…
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to validate the model based on bruises that where induced with…
The purpose of this study is to determine which patients undergoing cardioversion are at risk of AF recurrence, by associating plasma biomarkers and their overtime changes to AF recurrence after 6 months follow-up.
4.1 The main questionWhat is the effect of temporarily stopping PPI use on the stomach wall uptake of Tc99m Sestamibi with a myocardial perfusion?4.2 Sub-questions:- What is the relative maagwanduptake a myocardial perfusion Tc99m Sestamibi with…
Part I (cross-sectional study)1. To identify breathprints of VOCs by electronic nose in exhaled air that are associated with a bacterial origin of an exacerbation in COPD patients. 2. To examine the critical VOCs of these breathprints in exhaled air…
This study will assess the presence of prediabetes (defined as glycated hemoglobin [HbA1c] greater or equal to 5.7% and greater or equal to 6.4%, or fasting plasma glucose [FPG] greater or equal to 100 mg/dL [5.6 mmol/L] and greater or equal to 125…
The objective is to investigate the correlation between bacterial/viral gut infections and acute appendicitis in children.
The primary objective is to evaluate the lab transferability of the exercise model as used in the GRINTA! study. This will be achieved by comparing the effect of exercise on biomarkers in blood, urine and saliva in two different laboratories. These…
1. Optimize breath collection settings for optimal use in children.2. Evaluate the use of breath biomarkers for the prediction of therapeutic response in asthmatic children.
Primary objectives: To examine the ability of functional imaging signal changes over the course of treatment to distinguish patients with and without local recurrenceSecundary objectives:To examine the correlation between the different imaging…
Research into the influence of cooling on bruise development measured using reflection spectroscopy.
To determine the accuracy and robustness of this method it is necessary to validate it. In the past some successful studies have been performed in adult volunteerd. However we would like to investigate the influence of induced changes to the healing…