58 results
To investigate whether enhanced expression of growth factor receptors (FGF-R, PDGF-R and VEGF-R) and increasedvascular cell proliferation in the lung of IPF or PAH patients can be assessed using [11C]-Nintedanib or [18F]-FLTPET/CT imaging.
The purpose of this research project is to improve the overall quality and resolution of the MRI images, to correct for movement effects during the procedure and to speed up the investigation. The goal is to enhance and standardize a technique…
Main objective of the study is to define an algorithm based on the plasma biomarkers: A*40, A*42, t-Tau, p-Tau, NfL and APOE * status and NeuroCart tests, age, grip strength and level of education that distinguishes between positive and negative A*…
The primary objective of this study is to measure whether αvβ3 integrin expression and tracer uptake values of 68Ga-DOTA-(RGD)2 change in patients with (recurrent) low-flow vascular malformations after embolization therapy.
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.
To investigate whether atopic dermatitis patients can be stratified based on integral analysis of clinical patient data complemented by novel biophysical measurements, in-vivo Raman spectroscopy, microbiome swabs and a oral mucosa swab (one time).
The Imalife study aims to assess reference values of lung density, bronchial wall thickness, vascular calcification and lung nodules by quantitative low-dose CT. Secondarily, it aims to assess the relation of quantitative imaging biomarkers of the…
Primary:To evaluate the superiority of a patient-centred, education based, clinical strategy to reduce the volume of endoscopies for dyspepsia in patients over 18 years of age without alarm symptoms, referred for OGD through open-access endoscopy…
Purpose of the clinical study: To evaluate the effectiveness, safety and usability of real time continuous glucose monitoring (rCGM) in neonatal intensive care (NICU)Primary objective:* To evaluate the effectiveness of rCGM in the regulation of…
Development of blood-based monitoring techniques for treatment response evaluation and diagnostics in lymphoid neoplasms, including HL and NHL by using extracellular vesicle and cfDNA techniques for biomarker discovery, assay development and…
The main aim of this proof-of-principle project is to explore whether 1) standardized conditions (physical tasks, cognitive tasks and a combination of both) differing in task difficulty are associated with distinct physiological responses…
Primary objectives: - to determine the inter-observer variability of VLS- to determine the intra-observer variability of VLSSecondary objectives:- to determine the inter-observer variability of VLS per specific measurement location: antrum of the…
ICG allows continuous, non-invasive monitoring of the CO. ICG is a method that detects changes in thoracic electrical bioimpedance between simple skin electrodes, together with a conventional ECG. To estimate CO, it uses complex algorithms based on…
Primary objective: To determine the association between serum adiponectin and the risk of developing gestational diabetes. Secondary objective: To determine the association between serum leptin in pregnancy and the risk of developing gestational…
The objective of this study is to determine the changes over time of ASD symptoms and co-occurring psychiatric symptoms from childhood to adulthood and to investigate societal participation in adulthood, with an emphasis on education and employment.
Primary objectives: To assess the feasibility, accuracy and safety of preoperative SPECT/CT and intraoperative fluorescence imaging after administration of 111In-labetuzumab-IRDye800CW in patients with PC of colorectal origin who will undergo…
To perform a pilot study to optimise reproducible dynamic 4D CT scanning of the knee in evaluating patellar tracking and to reduce the radiation dose needed. The outcome of this pilot study will be used to perform a study on healthy subjects to…
Primary objective: To validate mpUS as imaging modality for detection and localization of prostate cancer by direct correlation of mpUS imaging and its parameters with histopathology of the resected prostate.Secondary objective: see Protocol paper,…
Primary Objective: 1: To determine the severity of respiratory problems, treatment modalities and outcome in the first year of life. Secondary Objectives:2a: To evaluate the course of respiratory problems and quality of life on long term follow-up.…
To proof that within the BR grade 3 ER/PR+ and HER2+ breast cancers the percentage of HRD is substantially higher in the metastatic lesions compared to primary breast cancers.