253 results
The primary objective of the study is to qualify an objective semi-quantitative CT scoring system lookingat the correlation between the relative change in the semi-quantitative CT score from baseline to week 6after DIILD diagnosis and the relative…
One possible reason why so many cancer patients with depressive symptoms indicate no care needs, could be that the offered care does not fit patients* symptoms, given the wide range of depressive symptoms (e.g. sad mood, fatigue). The objective of…
Primary Objective of the study: the agreement of the Free Style Libre Measurement with the laboratorium measurement and the AccuChekSecundary Objective: Delay of the interstitial glucose versus the Blood glucose measurements during an operation…
MOODSTRATIFICATION is a large, multi-center international study supported by the EU. Workpackage 3 aims to establish a proof-of-concept for a succesful therapy-stratification model for use in patients with a moderate to severe depressive episode.…
The aim of the project is to validate biomarkers for the development of a peripheral blood test which can distinguish early inflammation between various forms of IBD, with the use of novel techniques, such as mass cytometry and RNAseq.
In this study, the agreement between liquid biopsy and tissue biopsy based KRAS/EGFR molecular diagnostics will be determined. Additionally, pairwise comparison of different liquid biopsy based molecular tests will be performed based on several…
The primary objective of this prospective international multicenter diagnostic study is the comparison of the diagnostic accuracy between copeptin measurement after arginine-stimulation (CAS) and the current best diagnostic test copeptin measurement…
1. Explore the diagnostic value by comparing muscle volume, fatty infiltration and oedema/inflammation using qMRI in MG patients, healthy controls and MG mimics (other neuromuscular diseases and Graves* ophthalmopathy (GO) patients).2. Explore the…
Objective: The aim of this comparative study is to identify the highest value-based practice for ruptured intracranial aneurysm patients in the short-, medium-, and long term by prospective registration.
The aim of the study is twofold: 1) to determine the relationship between invasive (gold standard) and non-invasive techniques for measuring respiratory effort. 2) by means of gradations of snoring intensity, the relation between respiratory effort…
In the specified patient groups, quantitative outcomes will be compared in both weight-bearing images and non-weight-bearing images. In detail, the location, displacement and rotation of individual bone fragments in the foot will be measured in 6…
Exploration and possibly chaniging of the VBMEG method to analyse dynamic changes in the connectivity network in epilepsy patients. This study is a prerequisite to apply the VBMEG method to a larger dataset to possibly identify a quantitative…
The aim of this study is to evaluate the use of rapid IO-PTH measurement to predict post-thyroidectomy hypocalciemia.
Within the proposed study design it is possible to answer more study questions within the same population and within the same timeframe without adding much burden to the study participants. measurements and analyses will be performed both during a…
Effect of capillary blood collected in Hem-Col and kept at roomtemperature for 72 hrs on several routine laboratory parameters. The results of the tests are compared with the outcome of these tests when blood is collected by venapuncture and…
The primary objective is to study whether the (early prototype) sensors are able to reliably measure the vital signs they are designed to record. The secondary objective is to determine the feasibility and user acceptance of the (early prototype)…
The objective of the study is to set up and validate a digital neurotraumatology quality registry, to identify the most effective clinical care and to provide high quality evidence in support of treatment recommendations and guidelines.
Primary Objective: To investigate whether population screening for increased albuminuria among the Dutch population can contribute to the early detection of yet undiagnosed risk factors for renal and cardiovascular diseases in an early stage. For…
The main objectives of this study is to evaluate if EGFR positive cervical lymph node metastasis can be detected non-invasively using the MSOT Acuity Echo with cetuximab-800CW as contrast agent in patients with oral squamous cell carcinoma.
The aim of this study is to investigate the use of spirometry, forced oscillation technique (FOT), and negative expiratory pressure (NEP) in both protrusion and retraction of the mandible as prediction measurements for MAD success.