219 results
The focus of this study is to get more insight in the pathophysiology of IUGR. The main goal is to investigate the applicability of STIC in determining fetal cardiac function in IUGR.
We will investigate the feasibility of using STIC technology to evaluate the normal fetal cardiac anatomy and morphology in different stages of gestation. Further we aim at making normograms of different intracardiac parameters in relation to…
The primary objective is to investigate the influence of auditory and non-auditory factors on speech recognition abilities in quiet and in noise in CI users. For this reason we will study the effects of linguistic skills and working memory capacity…
Applicability of fetal brain imaging techniques for clinical purposes.
The aim of this MRI study is to understand how neurodegeneration in MS (in vivo) is related to other facets of MS pathology, i.e. inflammatory (T2) lesions, black hole (T1) lesions, cortical lesions and damage of the normal appearing brain tissue.…
We aim to observe in whole blood at patients core temperature and normotemperature how mild therapeutic hypothermia affects coagulation and in particular fibrinogen, in post cardiac arrest patients.
Assessment of microvascular alterations using orthogonal spectral polarization and correlate this with markers for endothelial cell dysfunction, fibrosis and histology in patients with renal function impairment who will undergo renal biopsy and…
The main goal of the proposed experiment is to provide evidence for the hypothesis that the adaptation range of posture control behaviour with only proprioceptive feedback is similar to the adaptation range with visual and tactile feedback also…
Assessment of the effect of kidney-pancreas transplantation in diabetic nephropathy patients on microvascular alterations using orthogonal spectral polarization and correlate this effect with markers for endothelial cell dysfunction and fibrosis
The primary objective is to determine if the incorporation of Multimodality MRI including MRGB within the Prostate cancer Research International for Active Surveillance (PRIAS) study for low-risk low volume prostate cancer leads to a higher number…
The key objectives of this study are:1. To determine by means of IENFD whether the PNS is involved in patients with autonomic complaints in MS. The obtained IENFD values will be compared with the age and gender matched healthy normative data,…
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
Assessment of the diagnostic accuracy of CTA for the detection of vasospasm after SAH in comparison to TCD.
Primary objective:1. To investigate the clinical value of [18F]Flutemetamol PET in memory clinic patients and especially those with suspicion of young onset dementia in terms ofa. change in (level of confidence of) diagnosis;b. impact on patient…
The main aim of the study is therefore to examine mu wave activity during observation, execution of movements and during movement imagery in comparison to a passive resting state and active relaxation condition in stroke patients and matched healthy…
The primary goal of the study is the prevalence of NRH in patients with IBD, who have been treated for at least five years with azathioprin or 6-mercaptopurin. A MRI of the liver, using the Seiderer protocol, and a percutaneous liver biopsy will be…
In this pilot study we investigate the use of these extra diagnostic tools. We also will use the results to see if these tools can diagnose cardiac events in patients that would otherwise be sent home
The objective of this study is to investigate if CEC are elevated in SCD (and if they could therefore serve as a potential tool for assessing SCD activity), and what the relation of CEC is to the patients medical history and to specific laboratory…
To determine the relation between tumor tissue phosphoproteomic profiles and progression-free survival (PFS) in patients with advanced RCC
To optimize the management of non-chronic shoulder pain in primary care by the introduction of ultrasound as a diagnostic triage tool. The following research questions will be addressed:1. What are the effects of diagnostic ultrasound and its…