40 results
End-of-life care involves high costs, but frequently fails in providing optimal patient centred care and quality of life. In the US, Advance Care Planning (ACP), a formalised process of communication about care preferences, has resulted in better…
The objectives of the study are:1) to give the laboratory a role in informing patients about their laboratory results, in order to meet the information needs of the patient2) to provide patients with validated (background) information with respect…
Primary ObjectiveTo evaluate the effect of a tailored behavioral change intervention comprising CBT and physical activity on participation (as measured by the DM1-Activ scale) for severely fatigued patients with myotonic dystrophy type 1 compared to…
Primary objective: To determine safety, feasibility, and the immune-activating capacity of short-term combined neo-adjuvant and adjuvant ipilimumab + nivolumab.Secondary objectives: To determine relapse free survival (RFS), any late adverse events,…
The primary objective of this study is to evaluate the effectiveness of an ESM-based intervention, called *Partner in Zicht* to increase spousal caregiver competence and feelings of control in managing daily challenges. Increased caregiver…
Is Mindfulness-based Stress Reduction (MBSR) feasible in older patients with mild cognitive complaints?
In this randomized controlled phase III study we will evaluate whether TIL infusion preceded by non-myeloablative chemotherapy and followed by high dose bolus interleukin-2 can result in an improved progression free survival when randomly compared…
The above mentioned developments are subject to the I CARE study. We hypothesize that general practitioner (GP) involvement improves both aftercare and preventive care resulting in improved quality of life and patients* satisfaction. Furthermore, a…
To evaluate the benefits, risks and costs of laparoscopic gastrectomy as an alternative to open gastrectomy (gold standard) as treatment for gastric cancer in a Western population.
Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) Study: a randomized clinical trial
Primary Objective: - To investigate whether a 12-week exercise intervention increases HRQoL in patients after curatively intended EC surgery compared to a usual care control group.Secondary Objective(s): - To investigate whether a 12-week exercise…
To establish (a) the prevalence and course of depression and anxiety in adolescents with type 1 diabetes and their parents/caregivers, (b) the risk factors predicting the presence of these emotional problems, (c) the care that is currently in place…
The study has two main objectives. The first objective is to estimate the extra yield in detected cases of AF in patients aged 65 years and over, using case finding. The second is to compare three methods to detect AF.
Primary Objective: To identify dropout rates at all stages of fertility care at the fertility centres of Isala in Zwolle, Erasmus MC in Rotterdam, Reinier de Graaf group in Voorburg, Elisabeth Twee Steden in Tilburg, the St Antonius Ziekenhuis in…
Knowledge on the magnitude of the decline and the pathophysiological mechanism can eventually help us topostulate an algorithm for well-balanced decision making in treatment strategies in the elderly CKD patients.This knowledge will be firmly…
We will investigate whether the Respecting Choices program will improve communication between patients and healthcare professionals, will improve the QOL and wellbeing of patients and their relatives, will reduce futile treatments and unnecessary…
We would like to research wether there is a difference in time of mobilization between women getting iv PCA with Morphine (PCA)as opposed to women getting continuous epidural analgesia (CEA)with bupivacaine and sufentanil.We expect that the PCA will…
The aim of the present study is: Primary objectives:1. To determine the health status of children and (young)adults with OBPI in terms of upper extremity function, daily activities, sports, participation and overall quality of life. 2. To determine…
The objective of the study is to dimplement and evaluate a new care path for elderly prostate cancer patients with complex care needs within 20 months. This will be done withinthe department of urology at the Meander Medisch Centrum at Amersfoort,…
The primary objective is to evaluate the effect of hospital-initiated and patient-initiated intensive follow-up on medication adherence in patients with chronic neuropathic pain.
The primary objective of this study is to assess the CV risk profile of Hindustanis without known diabetes mellitus (DM), hypertension, dyslipidemia or CV disease and evaluate the 10-year CV risk according to the Framingham risk score. Secondary…