48 results
The aim of this study is to identify barriers and facilitators for successful implementation of the care pathway, to ultimately inform national scale-up of the pathway.
To determine the waste reduction, net cost savings and environmental impact attained by redispensing oral anticancer drugs that go unused by patients compared with the standard practice of disposal.
The aim of this study is to obtain answers to the following main questions:1. Are delay discounting, time estimation and PTSD influenced by treatment?2. Do patients differ from healthy controls in delay discounting and/or time estimation ability? In…
In the STudying Ageing in Rheumatic diseases (STAR) project, our main goal is to: study the ageing process in patients with and without RA and specifically assess the impact of ageing on (1) the interpretation of commonly used measures of disease…
This study has been transitioned to CTIS with ID 2024-514588-24-00 check the CTIS register for the current data. Core Primary Objectives:1. To investigate the safety and tolerability of EP0042 given alone or in combination with anti-cancer…
In preparation for an RCT we want to test a combined lifestyle intervention for outpatients with chronic and/or severe mental health disorders in a feasibility study. We want to evaluate the feasibility and acceptability of our intervention and…
In this study we will assess the applicability of a digital intake in the Dutch colorectal cancer screening program in participants with a positive FIT who are referred for colonoscopy.
The current study aims to establish a database containing control data of TD children on a range of relevant domains for clinical neuroscientific research, including data on demographics, medical history, as well as neurophysiological, behavioural,…
The primary objective of our pilot study is to assess trial feasibility. Our secondary pilot objectives are to collect data on patient experience of healthcare, patient engagement, cost-effectiveness, and other data that might inform the design of a…
Primary Objective: What is the effect of a transfer from home to a nursing home environment on the level of physical activity in the elderly with dementia over time? Secondary Objective(s): Is there a relationship between a possible change in the…
Knowledge about which scanning behaviour is optimal, however, is mostly based on experiences and assumptions of professionals, and not supported by scientific literature and empirical data. Innovative techniques such as eye-tracking and Virtual…
Primary ObjectivesTo assess, as primary economic outcome measure, cost-utility of a personalised multimodal orthotic treatment approach to reduce the risk of plantar foot ulcer recurrence in diabetes.And, as primary patient-related outcome measure,…
1. To preserve testicular tissue of young boys with cancer with high risk of infertility for possible autologous transplantation in the future if infertility has become apparent, and to identify germcells in the testicular tissue.2. To gain insight…
To determine whether it is feasible in practice to optimally monitor and treat patients with COVID-19 (Utrecht: CA-ARTI) in the home setting by using an intervention that is widely supported in the region.
The overall aim of this project is to evaluate the effectiveness, cost-effectiveness and mechanisms of action of two psychoeducational interventions: a face-to-face nurse-led intervention called FOCUS+ and an eHealth intervention called iFOCUS.…
Primary objectives:To perform a study to:1. Estimate the prevalence of elevated albuminuria in subjects with a high risk of chronic kidney disease in the Netherlands.2. Evaluate which screening approach would be most effective based on costs per…
The objective of this study is to assess the clinical effectiveness of the PatientCoach mHealth app with and without home monitoring devices on sustained asthma control after AACT, in patients with severe or uncontrolled asthma.
This study has been transitioned to CTIS with ID 2024-513519-28-00 check the CTIS register for the current data. Primary objective • To compare the event-free survival (EFS) of neoadjuvant ipilimumab + nivolumab (followed by adjuvant nivolumab or…
To evaluate in SSc patients with low risk for disease progression 1) whether assessment in an outpatient clinic setting is an acceptable alternative for evaluation in the Care Pathway. Outcome parameters we will evaluate include 1) health care…
The primary endpoint (equal or improved MSQoL-54 and Eq5d) at which the value of telemonitoring is determined is t = 2 years.Mapping the effects of digital consultations or hospital visits, for MS patients, informal carers and the Isala…