3334 results
1. Is there a difference between the level of activities and participation among adolescents with chronic musculoskeletal pain as compared with the activity and participation level of adolescents not suffering from chronic pain?2. What is the impact…
The aim of the proposed research is to test, by the use of functional magnetic resonance imaging, the hypothesis that psychometric schizotypy (referring to, e.g., subclinical hallucinations in healthy people) is associated with reduced activation of…
The primary aim of the study is to identify breast cancer patients who experience objective and/ or subjective cognitive dysfunction one year after chemotherapy and find determinants of this cognitive dysfunction on patients' quality of life…
Study of the cost-effectiveness of fatigue management in patients with Crohn*s disease (CD)
The aim is to understand which individuals benefit from antibiotics.
To investigate whether an exercise-program that takes the patient*s level of exercise-self-efficacy into account, added to regular care, is more effective compared to regular care in increase the patients level of physical activity, improve…
In this study the efficacy of a novel monoclonal antibody on the development of psoriasis in the humanized mouse model will be investigated.This experimental compound will be compared with 2 registered drugs, i.e. Humira en Stelara.
To see if the new drug can prevent development of psoriatic changes in the transplant model of psoriasis
A pilot feasibility study (n=5) will be performed to evaluate the feasibility (logistics, timing) and safety of administering autologous tumor infiltrating lymphocytes (TIL) generated at the NKI-AVL infused in conjunction with systemic high-dose…
Primary objective:To identify the neural mechanisms via which oxytocin modulates social decision-making.Secondary objectives:- To provide an extension of observed behavioral effects of oxytocin on decision-making, specifically to examine decisions…
To optimize independent functioning and quality of life through:1. Systematic screening for increased risk of functional loss among community dwelling elderly (Phase 1);2. Providing a nurse-led, complex intervention to elderly people with an…
Please see pages 3-5 of the Protocol
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
Investigate how S1 and the premotor cortex modulate the cortico-spinal excitability as measures by single pulse TMS stimulation of M1.
In this study we aim to investigate the long-term results of the prepuberal orchidopexie for the acquired undescended testis. The volume and location of the testis are primary outcome parameters that display the result. This information will…
The aim of this study is to investigate the effects of an intervention focussed on the communication of the absolute 10-year risk to develop cardiovascular disease on risk perception, attitude towards a specific behaviour and the intention to change…
The primary aim of the study is to test the effectiveness of a collaborative care model for major depressive disorder for patients with DM, CVD, COPD, and HIV in the general hospital outpatient setting. Secondary aim is to estimate the cost-…
The primary objective of this study is to determine the long-term clinical course in patients who consulted their general practitioner 6 years ago with a new episode of knee complaints. The secondary objectives of this study are to determine…
The aim of this study is to determine whether subcutaneous administration of insulin detemir, as compared to NPH insulin, leads to a more pronounced effect on brain glucose metabolism and blood flow in brain regions associated with appetite…
The main objective of this study is to examine the incidence of psychosocial needs, anxiety and depressive symptoms at each time point, and to identify risk factors for worse short-term Quality of Life (QOL) in lung cancer patients and their…