28 results
This study aims to validate an integrated care model that is standardized and can easily be carried out in any other hospital.Primary objectiveThe primary objective is to determine the effect of a nurse-led, technology-supported, personalized care…
• To set up a national prospective observational cohort study of patients who have a hematological B-cell malignancy and are referred to the national CAR T-cell tumorboard for evaluation of eligibility for treatment with CAR T-cell therapy and to…
The aim of the project is to investigate whether the Nova contributes to cost-effective, client-oriented incontinence care for people with a profound disability, based on a cluster randomized study with a waiting list control group and a pragmatic…
Knowledge about which scanning behaviour is optimal, however, is mostly based on experiences and assumptions of professionals, and not supported by scientific literature and empirical data. Innovative techniques such as eye-tracking and Virtual…
Primary ObjectivesTo assess, as primary economic outcome measure, cost-utility of a personalised multimodal orthotic treatment approach to reduce the risk of plantar foot ulcer recurrence in diabetes.And, as primary patient-related outcome measure,…
The primary objective is to examine whether changes over time in monitoring measures of cognition and behavior are associated with functional outcomes in pediatric oncology groups. Additional objectives are to examine trajectories, risk factors, and…
To make an evidence-based recommendation on which method has the best efficacy (PROM), patient treatment experience (PREM) and safety profile (complications).
This study has been transitioned to CTIS with ID 2024-514588-24-00 check the CTIS register for the current data. Core Primary Objectives:1. To investigate the safety and tolerability of EP0042 given alone or in combination with anti-cancer…
1. To preserve testicular tissue of young boys with cancer with high risk of infertility for possible autologous transplantation in the future if infertility has become apparent, and to identify germcells in the testicular tissue.2. To gain insight…
In the STudying Ageing in Rheumatic diseases (STAR) project, our main goal is to: study the ageing process in patients with and without RA and specifically assess the impact of ageing on (1) the interpretation of commonly used measures of disease…
The aim of this study is to obtain answers to the following main questions:1. Are delay discounting, time estimation and PTSD influenced by treatment?2. Do patients differ from healthy controls in delay discounting and/or time estimation ability? In…
The primary endpoint (equal or improved MSQoL-54 and Eq5d) at which the value of telemonitoring is determined is t = 2 years.Mapping the effects of digital consultations or hospital visits, for MS patients, informal carers and the Isala…
This study has been transitioned to CTIS with ID 2024-513519-28-00 check the CTIS register for the current data. Primary objective • To compare the event-free survival (EFS) of neoadjuvant ipilimumab + nivolumab (followed by adjuvant nivolumab or…
Primary objectives:To perform a study to:1. Estimate the prevalence of elevated albuminuria in subjects with a high risk of chronic kidney disease in the Netherlands.2. Evaluate which screening approach would be most effective based on costs per…
The current study aims to establish a database containing control data of TD children on a range of relevant domains for clinical neuroscientific research, including data on demographics, medical history, as well as neurophysiological, behavioural,…
This study has been transitioned to CTIS with ID 2024-515514-40-00 check the CTIS register for the current data. The primary objective is to investigate the rate of pathological responses following different neoadjuvant immunotherapy combinations in…
This study has been transitioned to CTIS with ID 2024-511877-31-00 check the CTIS register for the current data. The primary objective is to demonstrate non-inferiority of experimental esketamine administration of 6x 1 day per 2 weeks (in total 3…
In this study we will assess the applicability of a digital intake in the Dutch colorectal cancer screening program in participants with a positive FIT who are referred for colonoscopy.
Primary Objective: To evaluate the *Triple Aim* performance of Care Pathway Technology for RA: - Evaluate and compare predefined RA health outcomes; Disease activity measured by DAS 28 joint score at baseline, month 12; RAPID3, HAQ-DI at baseline…
To assess whether the use of the personalized risk assessment tool (PERSARC) is (cost)effective in reducing decisional conflict and increasing informed choices in high-grade extremity STS compared to usual care (co-primary outcomes). In addition, we…