3877 results
There is at present a major focus on the role of the cerebellum in the pathophysiology of dystonia. It is speculated that the cerebellum is an hitherto overlooked yet fundamental part of the abnormal sensorimotor network that drives dystonia. This…
To investigate whether emotional arousal impairs facial emotion recognition in BPD patients and how specific borderline symptomatology is related with this.
The general objective of HELIUS is to describe (trends in) patterns of chronic conditions across six ethnic groups over time, and to unravel the causes of (the unequal burden) of chronic diseases across ethnic groups, with an emphasis on…
To gain more insight into the pathogenetic processes involved in SS by analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and non-inflammatory…
The aim of the study is to investigate the local levels of steroid-hormones compared to the peripheral levels in postmenopausal patients with endometrial hyperplasia, endometrial carcinoma and postmenopausal women without these diseases. This will…
to measure peripheral insulin sensitivity and intramyocellular concentrations of different FA metabolites (ceramide, gangliosides, diacylglycerol and triacylglycerol) known to interfere with the insulin signalling cascade during infusion of…
- Examine the reproducibility of the non-volitional endurance test in healthy subjects. The hypothesis is that the non-volitional endurance test is reproducible.- Comparing arm and leg muscle endurance in healthy subjects. It is expected that arm…
2.1 Primary Objective• Evaluation of the levels of thrombophilic factors in the blood of HIV-infected patients before starting with cART and the changes of these levels when on cART for the time of one year. 2.2 Secondary Objective• Evaluation of…
To evaluate the predictive value of microcirculatory perfusion for the incidence of Extracorporeal Membrane Oxygenation (ECMO) dependency and consequently survival. To evaluate the effects of vasopressor drugs and iNO on microcirculatory perfusion.
To observe the possible relationship between central, conventional hemodynamic parameters with relatively new peripheral, regional perfusion parameters in two versions of a model with controlled vasocontriction (cooling) - vasodilation (heating)
This study that documents the changes in heart rate, muscle sympathetic nerve activity, stroke volume and systemic vascular resistance in response to supine and head up tilted carotid sinus massage in elderly subjects.
In this study, we will assess whether healthy men with high-normal serum CK display attenuated platelet aggregation, compared to those with low-normal serum CK.
To investigate if jerks and psychiatric disorders in patients with dystonia are associated with a hyperdopaminergic/ hyposerotonergic system and whether reversal of a hyposerotonergic state has a therapeutic effect.
To collect maternal blood during the 2nd half of pregnany, in combination with clinical data and data on pregnancy outcome.
The aim of this study is to detect the hitherto unknown factors which possibly can explain the difference in acetylation. Therefore we need to collect blood from PPD allergic patients and healthy volunteers, to determine not only the genotype, but…
To investigate the relation between different autonomic function tests in critically ill patients.
Hypothetically, in patients with PBC or PSC the FGF-19 production or -response could be altered. The goal of this research is to study the FGF19 production after a standardized oral fat challenge and the effect of this FGF19 production on bile acid…
Primary objective:To evaluate variations of androgenicity and androgen (re) activity in (apparently) eugonadal females by using CAG repeat length polymorphism ([CAG]n) of the androgen receptor, free testosterone levels, 2D:4D ratio and attention for…
This pilot is meaned to obtain:- experience and understanding in the presence of new embolic load in the brain by means of DW-MRI- Understanding in the number of patients in which probably the post-operative DW-MRI can not be done according to…
This study aims to identify the specific environmental influences that cause discordance in neuroticism scores in MZ twin pairs. We hypothesize that the development of high neuroticism is due to having experienced more severe and longer lasting…