401 results
The first aim of this study is to examine differences in implicit and explicit learning in children born very preterm. The second aim is to test the alleged role of working memory and attention on (explicit) motor skill learning in preterm children…
The primary objective is to investigate quality of life after switch to a combination therapy including boosted DRV and DTG. Secondary objectives are to investigate 1) the residual viral replication, 2) level of virus production from infected cells…
The primary objective of the study is to provide natural history data onpatients with P-CID, irrespective of whether they undergo HSCT or not.The goals are to determine survival, the frequency of severe eventsand quality of life 5 years after study…
Primary objective:- To determine the residual *-cell function by measuring thedifferential response of *-cells measured by C-peptide and proinsulin secretion to various stimuli in patients with long-standing type 1 diabetes mellitus.Secondary…
The main objective of the study is to investigate if nicotinamide riboside supplementation can improve whole body and hepatic insulin sensitivity in overweight and obese men and women. As secondary objectives we want to investigate if nicotinamide…
Primary Objective: To determine the prevalence of A1AT-pathology by genotype analysis of patients with DD and comparing this to a population without DD.Secondary Objective:To determine whether the population with A1AT pathology develops more often…
This scientific study is intended to compare the safety and effectiveness of two stents, the Firehawk* stent and the XIENCE* stent. Both stents release a medicine. This reduces the odds of the blood vessel narrowing again. The Firehawk* stent is…
The aim of this study is to assess differences in the endogenous pain modulation paradigm in older and younger subjects, with and without an intensified sports regimen (ie. oarsmen).
The aims of the current study are to compare available tests for small airway function in asthmatic patients and to assess differences in small airway function between obese and non-obese asthmatic patients.
This protocol will compare clinical outcomes of the SUPRAFLEX and XIENCE drug-eluting stents in a broad patient and lesion population and will gain substantial additional information on patients in a real world setting. These data will also provide…
Primary Objective:To measure distances between the pointer tip held on surgical clips placed on the liver surface and the closest tumor border using navigation, and compare it to the actual distance measured in intraoperative XperCT. Secondary…
To describe the cognitive, physical and psychosocial factors of fatigue which may affect fatigue in patients with glioma.
The main objective of this study is to compare the function and phenotype of bone marrow HSPC*s in AMI patients to those of healthy control subjects.
Primary objective: study the association of circulating iNKT cell numbers and function with early atherogenesis, as measured by cardiovascular magnetic resonance imaging (MRI). Secondary objectives: a) study the association of circulating iNKT cell…
Original study:The proposed project will examine the effect of social learning in typical developing adolescents, by including brain structure, function and behavioural modelling in a typical developing age group.The main goal of this study is to…
1. Compare molecular signatures in six leg muscles using RNA-sequencing;2. Correlate these signatures to the muscle involvement pattern in three muscular dystrophies and identify regulators for muscle strength preservation
Primary Objective: To study alterations in metabolic balance in ALS patients and their impact on disease progression and survival.Secondary Objective(s): 1. To evaluate and compare the metabolic balance in patients with ALS and neurological control…
Main objective of this study is describing the functional morphology of the microcirculation of the endometrium.
Objective: to determine the comparability of the liver quantification using the Dixon MRI technique on the Siemens scanner with the MRS technique on the Phillips scanner.
Research Questions: Primary:1. Does a single night of short sleep reduce metabolic flexibility following a mixed meal challenge?2. Does a single night of short sleep alter the responsiveness of the HPA-axis?3. Are the disturbances of a single night…