380 results
The current study evaluates the OrthoSensor and investigates whether the combination of the Vanguard® Knee System with the OrthoSensor results in a faster recovery and better clinical outcomes during short follow up compared to conventional TKA (…
In recent years, we have identified a Dutch family and performed a large number of studies which have helped us gain insight into the disorder. (MEC protocols 02/223 and 03/140, Dissertation Van Rootselaar, 2006). We want to call on family members…
To determine the effects of hypercaloric HFHS snacking in the morning or evening on insulin sensitivity and serotonin function in the diencephalon.
The aim for this study is to investigate feces composition and postprandial effect, as done with oral fat loading test (OFLT), on endotoxemia (e.g. LPS and Ralstonia levels) in plasma as assessed with qPCR.
The aim of the study is to investigate the effects on time trial / cycle test performance after ingestion of Snelle Jelle 'kruidkoek' and water, banana and water, or only water.
In the proposed study, we will experimentally elucidate the effect of DBS on various critical dimensions of cognitive control including: the free will experience, instrumental learning, environmental change detection and working memory.
The first aim of this study is to examine differences in implicit and explicit learning in children born very preterm. The second aim is to test the alleged role of working memory and attention on (explicit) motor skill learning in preterm children…
To phenotype and genotype the population of patients with IVF in our cohort, and to find alternative diagnoses as a cause of the event of VF.
Evaluate the effect of menarche and menstrual cycle on the QTc interval among girls with genetically-confirmed mutations causing LQTS type 1 (LQT1) and type 2 (LQT2).
Objective(s): The primary objective of this study is to asses the dynamic vaginal pressure profile in two groups: 1) women diagnosed with dyspareunia and, 2) women with primary vaginismus. The secondary goal is to assess vaginal reflexes in women…
to compare in vivo total kidney 123I-MIBG uptake (by counts per pixel) by 123I-MIBG scintigraphy to direct ex vivo 123I-MIBG uptake of the flushed kidney as directly assessed with phosphor imaging.
The main objective of this study is to investigate the predictability of persisting post-surgical pain (PPSP) after TKA using electrical quantitative sensory testing (eQST) and nociceptive perception thresholds (NPT) in combination with a pre-…
Clarify the effect of 5T polymorphism with or without another CF causing mutation on the other allele, on the CFTR function.
Primary Objective: To investigate the clinical symptoms including pain response after third molar (i.e. wisdom teeth, or short: M3) extraction in relation to biomarkers and preoperative pain profile of individual subjects Secondary Objective: To…
To evaluate exhaled breath sampling approaches and their impact on results quality. To establish if sampling procedures impact specificity and sensitivity in extracting information of interest * in our case impact of garlic/fish oil supplements on…
The objective of this study is to evaluate the differences in exercise performance in healthy subjects, caused by the open-ended (CWR) en closed-ended (TT) character of the exercise test when cycled at the same absolute work rate. In addition, the…
the aim of this study is to compare the impact of an early-CR within 48 hrs. after PPCI to a late complete revascularization >2 weeks after PPCI on LV remodelling in patients with STEMI and multi-vessel disease.
to investigate whether the levels of a panel of biomarkers in dried blood spots can be used as a disease severity measurement tool in patients with AD, treated with topical steroids.
The main goals of this study1) To determine the prevalence of BE among first degree relatives of index patients in families that fulfil criteria for familial BE/adenocarcinoma of the GEJ2) Collect tissues of the index patients and all first degree…
To elucidate the changes in the timing of sleep and waking in different chronotypes (e.g. *owls* vs. *larks*) with at least 2 hours of social jetlag exposed to short wavelength (blue) light in the mornings upon awakening using Philips goLITE blu…