18 results
To evaluate whether healthy subjects and cocaine addicts carrying the s-variant of the 5-HTTLPR show improved reversal learning and reduced 5HTT function.
Primary objective:- To investigate whether a multi-component intervention strategy aimed at several vascular risk factors can prevent the occurrence of new cerebrovascular lesions in elderly non-demented subjects and if this correlates with…
To evaluate the value of volatile organic compounds analysis by eNose in the early detection of second primaries or metastasis (and early lesions).
To identify predictive variables correlated with percentage excess weight loss, reversal of metabolic complications of obesity and quality of life and postoperative complications; to identify metabolic variables correlated with markers of the…
To determine the effects of biphosphonates on radiation induced microvascular damage in the skin of breast cancer patients by comparing skin biopsies taken prior to and 4 months after treatment with a biphosphonate.
Main objective: 1) To investigate whether BAT activity differs between South Asians and Caucasians.Secondary objectives: 1) To investigate whether sympatic stimulation of BAT differs between South Asians and Caucasians2) To investigate the…
To determine the effect of hypoglycaemia on BAT-activity.
The primary objective is to elucidate the question whether historic HBV viral load (in samples taken from 1989 * 1996 during pregnancy) is associated with the risk of HBV-related cirrhosis or mortality in a cohort of non-Asian individuals with…
1. To make a phenomenological profile of BIID individuals using a standardized questionnaire.2. To perform whole exome analyses in four phenomenological identical BIID individuals.3. To perform molecular analyses in a series of other BIID…
The objective of this study is to gain insight in HIV infected children in the AMC in:.- the prevalence and clinical signs of livertoxicity - an association between the different compounds of combination anti-retroviral therapy (cART) and…
Primary objective is: - To evaluate the effects of (controlled) dehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to dehydration is mediated…
To identify pre-malignant lesions within the endometrium as precursor lesions of serous epithelial ovarian carcinoma.
Identifying the factors and underlying mechanisms involved in the pathogenesis of immune paralysis in trauma patients. Mapping the time-course of immune paralysis in trauma patients.
To determine the influence of a pure sensory polyneuropathy on balance correction in light of the first trial response and in light of multiple succesive identical perturbations, compared to healthy control subjects.
Primary objective is: - To evaluate the effects of dehydration and subsequent rehydration on coagulation and fibrinolytic parameters.Secondary objectives are:- To evaluate whether the response of coagulation and fibrinolytic parameters to fluid…
The objectives of this study are to investigate: - which strategies patients use to maintain gait stability and gait adaptability; - whether the strategies used by patients to maintain gait stability and gait adaptability, differ from strategies…
• To elucidate the role of noradrenaline in the mechanisms involved in human memory consolidation• Evaluate the levels of cortisol and 3-methoxy-4-hydroxyphenylglycol in the various points of a memory consolidation window• Define pharmacological…
•To determine the effect of hyperglycemic dysregulation on sleep characteristics (duration and quality), in patients with DM1 'What are the effects of controlled hyperglycemia on sleep characteristics (sleep duration and/or quality) in patients…