616 results
Assessment of triglyceride clearance in a FH population with variations in heparan sulfate biosynthesis.
The objectives of this study are to investigate: - which strategies patients use to maintain gait stability and gait adaptability; - whether the strategies used by patients to maintain gait stability and gait adaptability, differ from strategies…
The primary objective to our study is assessing functional outcome, quality of life, and genetic mutations in patients with a cloacal malformation. Functional outcome:- Colorectal functiono Objective: assessing colorectal function through the use of…
Hypotheses: - The nutrient sensing receptors have a different spatial distribution along the intestinal tract.- The receptors: T1R2/T1R3, SGLT-1, G-protein coupled receptor 120, T1R1/T1R3, Pept1, G-protein coupled receptor 93, calcium sensing…
Our primary objective is the effect of taurine on morbidity and consequent mortality.
The aim of this protocol is to invite the NeuroIMAGE cohort once more for a follow-up investigation and collect phenotypical, cognitive, and MRI data. This design offers the opportunity to examine by means of longitudinal phenotypic, cognitive, and…
To detect high-risk pathogenic mutations in germline DNA of children with childhood cancer that are suggestive of genetic predisposition, using NGS-based whole-exome sequencing, resulting in novel targets for future functional and translational…
The primary goal is to investigate whether there are deficits in the response inhibition and performance monitoring in cannabis dependent patients on both a behavioral and an electrophyisiological level. The secondary goals are to investigate…
To study the effect of early tumour development on brown adipose tissue activity
• To elucidate the role of noradrenaline in the mechanisms involved in human memory consolidation• Evaluate the levels of cortisol and 3-methoxy-4-hydroxyphenylglycol in the various points of a memory consolidation window• Define pharmacological…
Objective: General objective: To improve and standardize assessment of risk behaviour and its behavioural correlates in HIV patients. Specific objectives: 1) To assess sexual risk behaviour in HIV patients, 2) to assess drug related risk behaviour…
The project aims to gain more insight in the process of bonding between parents and prenature infants, to validate a screening instrument that can be easily adopted in maternity wards of (general) hospitals to detect parents and children at risk for…
The objectives of this initiative are:1. To establish the disease oriented biobank; processing and storage of blood and CSF specimens and health information of MS patients (which may include health records, family history, lifestyle and genetic…
To study the effect of thyroid hormone and thyroid-stimulating hormone on brown adipose tissue activity.
To elucidate the role of cortical inhibition in PGES (pilot).
Primary: 1. To determine what the effect of exercise on coagulation.2. Establish the changes in bloodcell counts as a result of exercise.3. What the effect of exercise is on the platelet function.4. To test the different effects of cycling and…
The AMSTAD-OCD study aims to contribute to the improvement of outcome in OCD by identifying the determinants of a chronic course.
To investigate LN cellular composition and functional aspects of lymphnodes in pre-clinical patients eventually developing RA compared to patients that do not develop RA, and of lymphnodes of early RA patients compared to non-RA patients, all…
To assess the effect of fitness training on movement efficiency, fitness level, physical activity and quality of sleep in ageing subjects
To examine the long-term effects of a CT- and/or RT-induced premature menopause on BMD, cardiovascular status, neurocognitive function and QoL in female HL survivors.