143 results
To get insight in the current care for mood disturbances after stroke, by identifying best practices and needs as experienced by patients and healthcare professionals.
Primary objective* To investigate the correlation between cutaneous microcirculation (using LSCI), finger and toe pressures and shunt flow in hemodialysis patients.Secondary objectives* To investigate the variability in basal flow measured with LSCI…
To assess utility and accuracy of an electroencephalography (EEG) -based brain network analysis platform as potential diagnostic tool for MDD, to correlate digital biomarkers and *gold standard* psychometric questionnaires such as MADRS in MDD and…
synopsis:Primary:• To assess the health related quality of life (HRQoL) through the MSQoL-54 scale in highly-active relapsing multiple sclerosis (RMS) subjects treated with Mavenclad® for 2 years (24 months)Secondary:• To assess treatment…
We aim to identify immunological parameters during (immune)therapy. We will study the effect of (immune)therapy on generic immune mediators and more specifically for NK cell, T effector and Treg cell functionality. Furthermore, we will explore DNX…
The primary aim of this study is to develop ecologically valid listening tests with realistic social consequences of speech understanding difficulties in which physiological outcome measures are applied. Specifically, we aim to develop a speech…
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
To enhance our knowledge concerning the effectiveness of tDCS in the rehabilitation of stroke patients. Next to this, the results will also contribute to our knowledge concerning the role of the parietal cortex in episodic memory and attentional…
The overall aim of this study is to identify developmental deficits in children with Rolandic epilepsy. If developmental deficits are observed, we hope to determine timing, persistence, and prognostic factors for developmental deficits and improve…
Primary Objectives* To assess the safety and tolerability of Foxy-5 in subjects with colon cancer.* To assess circulating tumour DNA (ctDNA) in plasma as a surrogate parameter for disease recurrences in subjects with Wnt-5a low colon cancer treated…
To investigate whether there are differences in single nucleotide polymorphism*s (SNPs), circulating tumor DNA (ctDNA), micro RNA (miRNA) and immune profiles between responders and non-responders to FOLFIRINOX chemotherapy and between patients who…
Primary objectivesIn a randomized control trial (RCT) the following hypotheses will be tested:1. The behavioral intervention with a baby carrier in the early postnatal phase results in different hormonal, neural and behavioral responses to infant…
Primary objective is to examine the effect of acetaminophen on the cardiac deceleration associated with the painful experience of social rejection.
The primary goal is to hasten drug development in FSHD by evaluating the usefulness of various outcome measures, validating new clinical outcome measures, and to elucidate cohort characteristics useful for determining eligibility criteria to improve…
Primary objectives: 1. . To study prevalence of NASH in unselected HIV-monoinfected patients assessed by Fibro scan. Secondary objectives:2. To identify risk factors for NASH in HIV infected patients compared to HIV-positive patients without NASH. 3…
Primary Objective: Investigate if a release of the EOM in patients undergoing a VHR with retromuscular mesh gives (long term) loss of function of the AW .
The aim of this explorative study is to lay the foundation for investigating the carryover effects in spinal cord stimulation.
To characterize the response to intradermal LPS by:- Clinical measures- Biophysical measures- Imaging- Molecular and cellular responses- Routine safety measures
The main objective of the study is to examine whether dynamic light has a positive influence on the sleep-wake rhythm, depression, emotional distress and agitation in people with dementia. Healthcare innovations, intended for at home use, are used…
This study will evaluate the effect of dose tracking in conjunction with reminder notificationsand motivational/adaptive messages over 24 weeks on treatment adherence behavior insubjects with COPD. The dose tracking is done by the Concept2 inhaler…