163 results
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of positive suggestions as measured by subjective pain intensity and itch ratings in response to validated pain (Cold Pressor Test) and…
To investigate the effect of dopamine-related genetic polymorphisms on resting-state fMRI measures of network functional and structural connectivity.
The aim of the study is to evaluate the change of lung function at least one year after definitive chemoradiation (concurrent or sequential) in patients with locally advanced (non) small cell lung carcinoma to assess late radiation injury in our…
Here we will test the hypothesis that stimulating DLPFC with either rTMS or tDCS during one single session affects the functional connectivity of the DLPFC, and is associated with an increase of activation in connected areas of the cerebrum and…
Protocol optimization for the GAITRite in m.3243A>G carriers
The primary objective of this study is to determine the equivalence accuracy of energy expenditure and resting heart rate measurement of newly developed software in reference to currently approved software. Secondary objective is to asses the…
This study will investigate the effectiveness of an interactive smart phone application that provides medication reminders and motivation to take up healthy activities during daily life, with the aim to improve schizophrenic and non-affective…
To provide evidence for the efficacy of Branched Chain Keto Acids (BCKA) and Branched Chain Amino Acids (BCAA) when compared with milk proteins to stimulate postprandial muscle protein synthesis in vivo in healthy older humans.
1. Determine whether different classes of epigenetic modifiers affect HIV-1-specific T cell immunity.a. Investigate whether HIV-specific T cell exhaustion can be reversed by inhibitors of different classes of epigenetic modifiers.b. Examine whether…
We aim to validate MRS with a cholinergic challenge as method to investigate muscarinic M1 receptor functioning. To investigate the relationship between the response to a muscarinic receptor antagonist with biperiden phMRI and [123I]IDEX SPECT…
To investigate the effect of cytomegalovirus(CMV)-infection on the production rate and death rate of T cells after influenza vaccination in elderly.
Primary Objective: The aim of this qualitative study is to obtain more insight into how patients with PVD perceive and evaluate management of their vulvovaginal complaints by their GP.Secondary Objective: Optimizing support and treatment by GP*s to…
Primary:To compare the number of critical errors made by COPD patients, after a subject has read the respective patient information leaflet(s) (PIL), for each treatment option tested.Secondary:Number of critical errors made after instruction from…
To determine the local and systemic immune profile, with emphasis on T lymphocytes, in pancreatic cancer patients; and monitor how these immune profiles are affected by treatment for individual patients.
* To investigate oculomotor and vestibular activity in individuals with RTT. * To compare oculomotor and vestibular activity with more functional eye gaze and communication skills. * To compare oculomotor and vestibular activity with severity of…
The main goal of the study is to optimize the perception of vocal characteristics through a cochlear implant. It will span a number of aspects: psychophysical characterisation, its relation to speaker discrimination, its relation to single voice…
To explore whether wearing the orthosis improves the performance of functional activities, additionally to obtain insight in the usability of the orthosis.
The objective of this project is to design and test a novel assistive device to ultimately prevent low-back pain in able-bodied workers and to support workers with low-back pain who are re-integrating in the vocational setting. In this project, two…
Original study:The proposed project will examine the effect of social learning in typical developing adolescents, by including brain structure, function and behavioural modelling in a typical developing age group.The main goal of this study is to…
The primary objective of this study is to investigate the association between changes of lean body mass and overall grade 2-4 toxicity during adjuvant chemotherapy in colon (or rectal) cancer patients.