50 results
To reduce the consumption of oral corticosteroids (OCS) in patients with severe asthma while maintaining asthma control, in order to decrease the incidence of long-term steroid-induced side effects and to improve quality of life (QoL). The specific…
The main objective is to explore what is going on in two brains at the same time while they are interacting with each other in a controlled fashion: during the game of charades.
The aim of this experimental study is to find out whether children and young adults with the DS have an altered pain sensitivity in comparison with children and young adults without cognitive impairement.
1) To determine the effects of caloric restriction on hypothalamic function in response to glucose ingestion in patients with type 2 diabetes mellitus.2) To determine the effects of weight loss on hypothalamic function in response to glucose…
In the present study we propose two TMS experiments, in which we want to examine the brain areas crucially involved in the processing of emotional prosody in healthy right handed subjects.
The aim of this pilot study is to evaluate whether precise HDsEMG-guidance improves the therapeutic effect of BTXA. Because of its minor functional importance and focused endplate distribution, the extensor digitorum brevis (EDB) muscle is selected…
Main objective Because this study will include young children (0-3 years old) the challenge is to measure isometric muscle force adjusted to their natural behavior. From 4 months old a child can pull a toy towards himself. Therefore we want to use…
HypothesisSexual function in female systemic sclerosis patients is impaired as a result of fibrosis of the genital tract, fatigue, chronic pain, Raynaud*s phenomenon and contractures. AimThe aim of the study is to investigate sexual function and its…
The main objective is to study the neural background of episodic bindings and pro active control with an event-related fMRI experiment.
To compare the development of sensory specific satiety for sweetness after consumption of energy containing and low energy soft drinks. Moreover, we investigate whether SSS depends on the method of administration / oral processing, which influences…
In this study, an attachment theoretical perspective will be used to investigate the predictive testing process for hereditary, neurodegenerative disorders (Huntington*s Disease, CADASIL, HCHWA-D, FTD) and hereditary cancer syndromes (hereditary…
The purpose of this study is to investigate the role of dopamine in learning about sexual reward in healthy females. We suppose that repeated associations between a neutral stimulus and sexual stimulation results, through classical conditioning, in…
To gain insight into the prevalence of HBV and HCV and risk factors for HBV and HCV among (former) tatooists and piercers and individuals with multiple tattoos or piercings.
The primary objective is to evaluate the neuro-endocrine stress response during ETS training.The secondary objectives are to assess whether chronic stress, individual sensitivity and personal experience with trauma or disaster medicine are…
The present study aims at exploring a visuo-tactile mirroring mechanism in patients with autism. Furthermore, the relationship between neural tactile simulation processes, empathic abilities, and symptom severity in the social domain will be…
Objective: To determine whether genotype of the promoter polymorphism is associated with alterations of mRNA expression of the M2 receptor
The main objective of this research is to disentangle the neural mechanisms involved in two important forms of learning: trial and error individual learning vs. learning by observation.
Our primary objectives are to evaluate - if endogenous EPO, EPC levels and EPC function are different in patients with stable and unstable CAD, compared to age and sex matched controls;- if a correlation exists between endogenous EPO and EPC levels…
In our own recent studies we found indications of the existence of particular executive functioning deficits as well as memory impairments following different regimens of cytotoxic agents. Together with the indication from our animal study of a…
To study the spread of STI among heterosexual males and females (heterosexuals) in Amsterdam in order to provide information for building evidence-based prevention strategies and to evaluate existing control programs. Three substudies are part of…