19 results
1) To perform gene mutation analysis in family members of patients carrying a proven mutation in the candidate gene.2) To determine the clinical, biochemical and radiological characteristics of carriers of a mutation in the candidate gene.3) To…
The aim of the study is to strengthen the basis for a new application of pupillometry (i.e., the measurement of pupil dilation) within the field of Audiology. An innovative method to quantify listening effort (pupillometry) will be further developed…
Primary objective is to compare physical activity (time spent in moderate to vigorous activity and physical activity level) and exercise capacity (VO2 peak) in children after OLT with published data of healthy controls.Secondary objective is to…
The proposed intervention aims to increase sport participation of youth with behavioural and/or learning problems as part of their youth care program within a Rotterdam youth care organisation. This will allow us 1.) to empirically test the effect…
Primary Objective To evaluate the gastric emptying time of the protein hydrolysates PRO+CHO beverage in patients with a delayed gastric emptying and compare this with the gastric emptying time of healthy subjects (PrePro1) Secondary Objectives To…
The primary objective of this study is to investigate the neuro-endocrine development of socio-emotional control related to automatic and defensive action tendencies and how this contributes to social interactive behaviour across adolescence and…
To investigate whether the occurrence and severity of neurological withdrawal symptoms during a discontinuation trajectory of antipsychotics used for challenging behaviours in people with intellectual disability is associated with achievement of…
Determine whether the prevalence of allergic sensitilization, defined as at least one allergen specific IgE with a concentration of >= 0,35 kU/l, is lower in people with than without DS. Analyse whether this prevalene is depending on age, how…
The aim of the study is to determine whether prenatal and current exposure to environmental chemicals is associated with developmental outcome in adolescents. We will investigate whether this exposure is associated with the thyroid hormone…
Evaluate the effect of menarche and menstrual cycle on the QTc interval among girls with genetically-confirmed mutations causing LQTS type 1 (LQT1) and type 2 (LQT2).
To determine the appropriateness of scale content of the preliminary CLEFT-Q scales by age and culture and to identify unclear or ambiguous items, instructions and response options
Primary Objective: *Which outcome measure should we use to measure disease severity and disease progression in this specific group?*To test the feasibility (% of patients who were able to complete the test) of the selected outcome measures.To test…
The objective of this study is to identify the effect of musical experience and training on the perception of speech in quiet and in noise, as well as on perception of music-related stimuli, such as, pitch, timbre, emotion and melody recognition, in…
The aim of the present study is to investigate the reproducibility of upper extremity strength measurements in children with CP. The following strength measurement instruments will be studied: Hand Held Dynamometry (HHD), pinch- and grip strength…
To collect demographic, clinical, therapeutic, microbiotic and imaging data in patients with JIA, to build a repository, to find novel biomarkers and to construct computerized models to predict the prognosis in children with JIA af the time of…
Primary objective: To assess microbiological, immunological, genetic, clinical, cognitive-behavioral, and epidemiological determinants for development of persisting symptoms in both adult and juvenile Lyme patients, and establish prediction rules *…
The main objective is to assess hallmarks of protective and waning immunity to vaccine preventable and non-preventable viral and bacterial diseases.in cases of various age groups and age-matched healthy controls. Secondary objectives are 1) to…
In the current proposal, two primary objectives will be addressed. The first is to establish the spatial correspondence between fMRI, ECoG/stereo-EEG and ECS for different brain functions in children. The second is to investigate the feasibility of…
At the brain system level, we seek to investigate whether neural response patterns obtained by fMRI, MEG EEG, t(A/D)CS and fNIRS can reveal the neural and physiological mechanism behind cognitive processes in general, more specifically per study…