521 results
We hypothesized a beneficial effect of IUI in couples with an isolated cervical factor. Furthermore we hypothesized that the post-coital test can identify those couples who would benefit from IUI without ovarian hyperstimulation.
1-2 intramuscular injections with 100 mg dexamethason in persons without arthritis but with elevated serum levels of rheumatoid factor and or anti-CCP will lead to a reduction in antibody concentrations after 6 months and possibly to a lower…
A late intensification course (VIMARAM) improves the outcome of infants with acute lymphoblastic leukemia.
MPS I patients can be treated with Aldurazyme safely and effectively.
Pre- and probiotics are able to change the composition of the altered intestinal microbiota that is found in allergic patients, indicating beneficial effects of these nutritional components in the prevention and treatment of allergic diseases. The…
1. Regular physical follow-up can partly be replaced by nurse-led telephone follow-up, with at least similar quality of life (QoL), in breast cancer patients treated with curative intent. ( change in QoL < 5 points) 2. An informative/…
The experimental group 2 (addition of action plans) will outperform the experimental group 1 (no action plans) with 10% at the last post-test after 12 months.
Care providers are more likely to adhere to clinical practice guidelines when they receive guideline-based decision support by an electronic system.
In this study, we expect to decrease the number of referrals and repeat smears by immediately referring those women who are positive for hrHPV with mildly abnormal smears for colposcopically-directed biopsies. Thus, for the remaining women with BMD…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
1. What is the effect of Cognitive Behaviour Therapy in severely fatigued disease-free cancer patients on fatigue, functional impairment and psychological well-being, compared to patients waiting for this treatment? 2. Is the effect of Cognitive…
To compare FDG-PET and CT-scan for the early prediction of non-response to preoperative chemoradiotherapy in patients with potentially curable esophageal cancer.
Caregivers' sense of competence will improve significantly more in participants of the intervention group compared to the participants in the usual care group.
To determine the cost-effectiveness of CBT compared to care as usual in patients with a recent onzet of schizophrenia, who suffer from persistent and recurrent symptoms of psychosis.
The AMSTAD-OCD study aims to contribute to the improvement of outcome in OCD by identifying the determinants of a chronic course.
Explore the efficacy, safety and tolerability of oral R129160, 60 mg o.d. in patients with chronic idiopathic urticaria
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
Enzyme therapy with recombinant human alpha glucosidase results in prolonged survival; improvement or stabilisation of cardiac hypertrophy and function, improvement or stabilisation of pulmonary function and improvement or stabilisation of muscle…
Patient with incurable disseminated left-sided colonic cancer are better palliated by colonic stenting than surgery measured by hospital free survival in "good health"(WHO-score 0 or 1) Colonic stenting is cost effective in patients with…