1600 results
Simvastatin (an HMG-CoA reductase inhibitor) induces apoptosis in vitro and sensitizes the myeloma cell to chemotherapy. This is the first clinical trial to test if in vivo there is the same sensitization in relapse or refractory multiple myeloma.
1. Daily home monitoring of exhaled nitric oxide (FENO) in patients with severe asthma facilitate tapering of oral corticosteroids to the lowest possible dose, leading to a reduction of total corticosteroid consumption; 2. This can be achieved…
A single, prophylactic dose of dexamethasone during cardiac surgery reduces the incidence of major postoperative complications.
Treatment with Infliximab will reduce loss of visual acuity by 8 letters or better on the ETDRS chart.
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ETMI increases the detection rate of early neoplasia in BE patients with 40% or more compared to standard video endoscopy
This is a superiority trial testing the hypothesis that adenoidectomy is more effective than a watchful waiting strategy in children with recurrent upper respiratory tract infections.
Does sildenafil improve tumour perfusion?
The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent…
What is the relation between disease activity, treatment, and metabolic syndrome / insulin resistance.
To identify candidate antigens for the development of a prophylactic Staphylococcus aureus vaccine by studying expression profiles of host and pathogen determinants during natural infection.
Multiple pregancies can be prevented without loss of pregnancy rates by treating couples with manipulated natural cycle IVF or with IVF-eSET plus cryo-cycles instead of standard treatment with intra-uterine insemination and controlled ovarian…
The use of 800 mcg of misoprostol prevents manual removal of the retained placenta in 80% of cases.
Intraneural injection of anesthetics in upper and lower extremity blocks increases the risk of neurological damage.
MMR vaccine administered intramuscularly induces the same adverse effects and immunogenicity as subcutaneously.
The aim of this study is to prove the efficacy of 3 times daily 1 mg glycopyrronium bromide admixture versus placebo admixture in patients with PD with hypersalivation. Furthermore, the safety of glycopyrronium bromide used in the mentioned dosage…
To investigate the effect of low dose oral silicon as an adjunct to calcium/vitamin D3 on markers of bone turnover and BMD.
What is the short- and long term effect of preventive interventions that are advised on the basis of the results of the RSI QuickScan with respect to the decrease of the risk factors, RSI complaints and absenteeism due to these complaints? What is…
Exploratory study to investigate the effects of TNF targeted therapy with infliximab on the synovial cell infiltrate, and the induction of apoptosis.
Etanercept is able to improve clinical and functional abnormalities and to halt or reverse radiographic changes in inflammatory erosive hand osteoarthritis by virtue of blocking a major pro-inflammatory cytokine, tumor necrosis factor (TNF).