2170 results
The main objective is to investigate whether ionized magnesium concentration varies during one day, and whether it is changed after one bout of exercise.
We aim to evaluate the efficacy and applicability of a CBT intervention for relevant persistent comorbid OCS in patients with a psychotic disorder. We hypothesize that 1) CBT of comorbid OCS will result in a clinical relevant reduction in severity…
The purpose of the study is to investigate the optimal dose combination of both drugs in healthy volunteers who will undergo a pain test.
n 2 out of 3 previous clinical studies a granule formulation (powder) of GRC 17536 was investigated and in 1 study various tablet formulations of GRC 17536 were investigated. The results from these studies showed that GRC 17536 is absorbed better…
The purpose of this study is to obtain blood samples from up to 14 subjects who previously received namilumab in the previous study M1-1188-002-EM (PRIORA, [NCT01317797]) to correlate genetic markers with clinical outcomes.
To evaluate the effects of JNJ-42847922, compared to zolpidem and placebo, on driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) after forced awakening using a validated driving simulator test at…
To assess the effect of CAC with effective temperature on pain sensation and consumption of narcotics in patients operated for TKA after 7days postoperative compared to CAC without effective temperature.
To determine the effect of RIPC of the upper limb on the inflammatory response during human endotoxemia (infusion of LPS), as well as the additional effect of 7-day RIPC compared with single-dose RIPC.
To assess the diagnostic value and feasibility of CFR measurement by TTDE as compared to invasive measurement (Gold standard).
To determine the degree of recurrence of contractures in the thumb, caused by Dupuytren'Disease after treatment with CCH
Main objective:To evaluate the non-inferiority of switching to the FTC/RPV/TAF FDC as compared to continuing FTC/RPV/TDF FDC in virologically suppressed HIV-1 infected subjects as determined by maintaining HIV-1 RNA < 50 copies/mL at Week 48…
Determine the gastric and neural correlates of bloating.
Our aims are to identify the clusters of impairments in cognition, behavior, quality of life, and fatigue in children after anti-NMDAR encephalitis, to identify risk factors affecting functional outcome and to assess the progression or remission…
1. To explore the pharmacokinetics (PK) of intra-vaginal delivery of gonadorelin and oxybutynin. 2. To assess the safety and tolerability of gonadorelin and oxybutynin delivery with a prototype intra-vaginal ring.
To define a dose-response relationship after intrinsically labeled milk protein ingestion on myofibrillar and mitochondrial muscle protein synthesis after a single bout of endurance exercise.
The purpose of Part A is to investigate how safe the study compound is and how well the study compound is tolerated. The study will also investigate how quickly and to what extent the compound is absorbed into and eliminated from the body (this is…
Objective: The aim of the present study is to investigate whether additional titration on surface electromyography (EMG) of the diaphragm and intercostal muscles improves outcomes of chronic NIV in patients with COPD and stable CHRF in terms of…
The objective of the study is to investigate whether discontinuation of inhaled corticosteroids (ICS) for patients without a clear indication for ICS according to current guidelines results in a reduction of ICS use without adverse health effects…
The aim of this study is to investigate the efficacy and safety of minimally invasive surgery after five year follow up in a cohort of patients with symptomatic, drug refractory, paroxysmal or persistent AF. The patients will have an additional…
To determine if total joint arthroplasty leads to better results than trapeziectomy in the long term, with subjective and objective outcome measures.