2170 results
Primary Objective: • To demonstrate that changes in blood pressure and cerebral perfusion (induced with paced breathing and the Cold-pressor test) can be assessed in the MRI using the combination of NIBP and rapid ASL measurements. Secondary…
1. To investigate the relative contributions of different ocular abnormalities to the visual function.2. To investigate the precise relationship between ocular pigmentation and the development of the visual system abnormalities.
The primary objective of this study will investigate the effect of oral levosimendan on the respiratory function of patients with Amyotrophic Lateral Sclerosis.
The aim is to establish substantiated limit values based on the results of this study for tests used to determine driving ability in another study conducted with Cat. III drug users.
Main objectives Part 1• To evaluate the safety and tolerability of a single oral dose of HTL0018318, administered at one of at least three ascending dose levels (maximum of 8 ascending dose levels), in healthy younger adult male subjects.• To…
Primary objective: - To determine the accuracy of sCTA compared to DSA in the visualisation of the degree of occlusion in the FU of intracranial aneurysms treated with Surpass. Secondary objectives:-To determine the accuracy of sCTA compared to DSA…
The primary aim of this study is to determine the functional effects of RELM in healthy older males and females. The secondary objective of this study is to determine if there is a gender effect present in the level of RELM in older adults.
In the current study, we intend to study the diagnostic accuracy of promising urine biomarkers for early detection of acute kidney injury in patients undergoing major general surgery. The study is designed to validate earlier findings in a large…
The study will be performed in 3 parts, Parts 1, 2 and an optional Part 3. The purpose of the study is to investigate to what extent ODM-108 is tolerated. It will also be investigated how quickly and to what extent ODM-108 is absorbed and eliminated…
The objective of the study is to investigate the bioequivalence of 2 different proteins with regards to bioavailabillity in healthy elderly after one oral bolus intake.
The aim of this study is to explore whether subjectively experienced SB can be objectively assessed using computerized vision based analysis of motor performance upon awakening. Secondarily, patient experiences and data quality of the assessment…
We aim to determine whether cortical inhibition is changed with age and to determine whether the amount of inhibition and associated activity are associated.
The primary objective is to describe the clinical characteristics of infantile FSHD. The secondary objectives are: - To determine the incidence and prevalence of infantile FSHD- To describe the genetic characteristics of infantile FSHD. - To…
The main aim of the TRACE-BIOME study is to characterize the role of biomarkers related to the microbiome-gut-brain pathways in the effect of an ED as a treatment for ADHD.
To provide evidence demonstrating that ACT-guided heparin management during pulmonary thrombo-endarterectomy (PTE) involving cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) will result in inadequate heparinization and…
To determine appetite responses to different odors (signalling different food products), measured by appetite questionnaires, a food preference task, saliva production and food intake
Our objective is to investigate how individual finger movements are controlled within a sequential task. To study the presence and changes over time of motor overflow, multi-channel EMG on both intrinsic and extrinsic hand muscles are used. Changes…
We aim to study the role of PVAT in regulation of vascular function, tissue perfusion and glucose uptake in muscle. We hypothesize that PVAT determines insulin-induced vasoreactivity when studied ex vivo and correlates with insulin-induced…
Comparison of the size and shape of the ablation zone of liver tumors with the simulation results of the CllnicIMPPACT software environment
The aim of this study is to determine the time of incidence of TBI, by measuring the concentration of the biomarkers in CSDH and to investigate which method can be applied to determine the age of CSDH with hemoglobin derivatives.