2170 results
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
Metabolic disturbances associated with critical illness may disturb secretion of melatonin, the most important factor for circadian timekeeping. This disturbance may in turn hamper distribution and high quality sleep, with potentially detrimental…
To determine the effectiveness of guided CBT compared to care-as-usual in treating insomnia in the general practice.
Combining FOLFIRINOX chemotherapy and stereotactic radiotherapy can lead to better regional tumor control and better overall survival in patients with locally advanced pancreatic cancer.
Implementation of a practice guideline for optimal symptom relief in Dutch nursing homes will reduce suffering in patients with dementia and pneumonia.
It is hypothesized that an intervention with the KPR could decrease pelvic tilt, as measured using clinical leg length difference and the ASIS-PSIS angle, for 50% or create a crest height difference smaller than 0.5 centimeters in patients with non…
First, non-invasive diagnostic tools can optimize the diagnostic strategy, in order to minimize the number of invasive diagnostic procedures. Second, invasive imaging of the pulmonary artery can further differentiate the mechanisms involved in PH…
The aim of this study is to compare clinical outcomes and cost-effectiveness of two procedures for skin sparing mastectomy with implant reconstruction in a randomized clinical trial. The currently preferred two-stage breast reconstruction with…
The objective is to study the effectiveness of the online self management training Reuma Uitgedaagd! voor adults with a rheumatic disease.
The fall risk application of Gociety® is a valid method to identify fall risk profiles among elderly.
The aim of the study is to explore the relation between frailty, functional status and other patient characteristics and adverse outcomes as functional decline, length of stay, admissions and mortality. Frailty is multifactorial and is known to be…
A bundle of inexpensive interventions can reduce the emergence and spread of carbapenem non-susceptible Gram-negative bacteria in a low-resource ICU.
To assess the safety and tolerability of intravenous (IV) infusion doses and infusion dosing methodologies of ABP-700 alone or in the presence of pre-medications commonly used in the monitored anesthesia care (MAC) setting
that deeper neuromuscular block gives less pain and better surgical conditions during laparoscopic surgery
There are no differences in clinical treatment outcome between mechanical debridement alone or mechanical debridement along with use of Delmopinol for a time period of 3 months in treating peri-implant mucositis.
We hypothesize that the commercially available CE-marked over the scope Pro-select Padlock clip is able to clip a gastic/duodenal SET, where after full thickness resection of the SET can be achieved using a normal
A behavioural intervention will improve hand hygiene baviour and prevent the transmission of hand foot mouth disease
Surveillance using a molecular stool test could serve as an alternative for the current method that is based on colonoscopy
In the proposed study we will investigate the effectiveness of an online self-help intervention for people living with HIV and depressive symptoms in a randomized controlled trial. Additionally, moderators and mediators of treatment outcome will be…