44 results
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
Patients prefer naratriptan over paracetamol 1000 mg for the acute treatment of migraine attacks.
Primary: 1. To compare in inpatients with psychotic depression the antidepressive efficacy at seven weeks of three treatment arms: [1] 7 weeks venlafaxine (maximum dose 375 mg); [2] 7 weeks imipramine (dose adjustment to adequate plasma levels of…
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Patients prefer rizatriptan over ibuprofen for the acute treatment of migraine.
Findings from both epidemiological and basic research point to the possibility that NSAIDS impede the deterioration in schizophrenia.
The primary objective of the current study is to investigate the effectiveness of MCP-ED in a clinical sample of adolescents with an ED. As a result, this study will provide critical information about the potential relevance of implementing MCP-ED…
Implement BBB-ASL at VUmc and assess the reliability and reproducibility of f measurements in healthy volunteers and patients with glioma
We aim to investigate the efficacy of a novel eating disorder prevention program, the Diabetes Body Project, specifically targeting young females T1D. Firstly, we will test the hypothesis that Diabetes Body Project will produce significantly greater…
Main research question and primary objective: What is the effect of exposure to high vs. neutral temperature (32* C vs. 25* C) in combination with high vs. low humidity (30 %RH vs. 70 %RH) for 8 hours on cognitive performance?Secondary research…
Objective: to investigate areas of uncertainty about a possible future definitive RCT using AF-EMDR as an add-on intervention to a Smoking Cessation Program (SCP), by determining:• Feasibility/process outcomes (e.g. recruitment, adherence, treatment…
The aim of the present study is to assess whether the postprandial glucose response of the new test products is superior to the postprandial glucose response of an original treatment option.
As highlighted, significant gaps in knowledge remain regarding etiology of cough, consequences of cough and appropriate treatment of cough in patients with pulmonary fibrosis. A further understanding of the similarities and differences in cough…
Primary objective is to investigate the effect of VR on patient-reported pain outcomes in the ED. Secondary objectives are to investigate the effect of VR on analgesics use, patient-reported outcomes, and process indicators and to identify barriers…
In this study we compare the results of blood sample analysis when blood samples are collected in different tubes from different manufacturers.
Primary Objective- Evaluate longitudinal intra-individual and inter-individual variability of PBMC biomarkers in healthy participants:o LRRK2 protein (pg/mL)o total protein (ug/mL)o pS935 LRRK2/total LRRK2 peptide ratioo pRab10/Rab10 peptide ratio…
The main objectives of the study are to investigate if sleep positional therapy, using the LEFT smartwatch app, reduces nocturnal gastroesophageal reflux symptoms and can train patients to avoid sleeping in right side position.
To examine whether the neutrophil immune profile of healthy geriatric volunteers (age > 70 years) differs from the neutrophil immune profile of young healthy volunteers (age 20 to 25 years).
The primary objective is to investigate the effect of a 3 week intervention with either 1.,3 gram or 2 gram of GOS on the abundance of the genus Bifidobacterium in faecal samples in healthy women of 40 - 70 years old. The secondary objective is to…