33 results
Primary research questions:1. Does tinnitusspecific- behavioural exposure-treatment (T-BET) decrease tinnitus-related fear, tinnitus-severity and enhance recovery, when compared to a masking-therapy with use of personalised on-ear masking-devices,…
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
Patient with incurable disseminated left-sided colonic cancer are better palliated by colonic stenting than surgery measured by hospital free survival in "good health"(WHO-score 0 or 1) Colonic stenting is cost effective in patients with…
The aim of the study is to examine the effectiveness of Rock and Water (R&W) and possible moderators and mediators. Effectiveness: - The R&W program will increase students’ socio-emotional adjustment (i.e., psychosocial wellbeing,…
1. Welke rokers hebben baat bij welke transmurale “stoppen-met- roken- interventiestrategie”?; 2. Wat zijn de effecten van de verschillende “stoppen-met- roken- interventiestrategieën”?
Speech understanding with a speech processor fitted using the parametric fitting procedure and the recipient's own fine-tuning is as good as with a conventional fitting. The parametric fitting is more patient friendly and less time-consuming.
Informal caregivers in the experimental group are expected to be more satisfied with the care provided to them and the patient they take care of, to experience a less heavy burden, and to have a better health compared to the informal caregivers who…
A disease control of 60% is expected and will be clinically relevant with a lower reference bound of 45%.
The majority of adolescents in the Netherlands has an inadequate consumption of fruit, vegetables, fibers and an excessive consumption of energy-dense, nutrition-poor foods. Unhealthy diets result in an increased risk of overweight, obesity and…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
Multi-centre open label clinical trial.
Intrathecal methylprednisolone reduce the features of central sensitization in patients with complex regional pain syndrome type 1 having symptoms longer than 6 months and shorter than 6 years.
Chronic sleep disorders are associated with dysfunctioning during the day. Circadian rhythm disorders are a frequently occurring cause of chronic sleep disorders. The time at which the endogenous melatonin production starts to rise plays a key-role…
N/A
The effect of the TDM strategies on the viral load in terms of change from baseline (start or switch of therapy) to 96 weeks.
Acutely hospitalized older patients frequently suffer from inadequate sleep. Insufficient sleep can lead to patient distress and delayed recovery from acute illness or a surgical procedure. Currently, no evidence-based treatments exist for sleeping…
Intermittent androgen deprivation using CPA oral monotherapy improves the overall quality of life while achieving similar control of tumour growth to that attained by continuous CPA treatment.
1. A decrease in cocaine use over a three month period in participants who receive AAT training as opposed to VPT training. 2. A change in symptoms involving craving, the urge to use, withdrawals well as stated readiness to change in participants…