3161 results
This study is therefore aimed at quantifying the relative contribution of the two major receptor systhems involved in S(+) ketamine and methadone induced analgesia and side effects( respiratory depression,sedation,miosis).
Pyridostigmine will activate the parasympathetic cholinergic anti-inflammatory pathway and therefore reduce inflammatory signs and symptoms in patients with complex regional pain syndrome.
By using a proactive approach (prompts) compared to a reactive approach CT (computer tailored) program use will be increased by 20 %.
A preconditioning program with a gradual increase of biomechanical load, prior to the start of a training program, will result in a reduction in running related injuries in novice runners compared to the control group.
Research questions: 1. What are the effects of the addition of preventive CT to AD compared to AD alone in remitted patients with recurrent MDD with a follow-up of 15 months-24 months on: A. Time related proportion of depression recurrence; B. The…
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First-In-Human Clinical Investigation to evaluate the safety and performance of the Adagio Medical PFA and PFCA Systems in the ablation treatment of symptomatic Persistent Atrial Fibrillation (PsAF).
General objective:To develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy (OAT) who have been safely anticoagulated without bleeding or venous thromboembolism (VTE) recurrence for 6 months since…
It is hypothesized that aerobic exercise therapy (AET) and cognitive behavioural therapy (CBT) are both effective in improving activities and QoL in patients with Amyotrophic Lateral Sclerosis (ALS) compared to the usual care.
Binocular patching in combination with posture adherence is superior to posture adherence alone in achieving visualization of the superior fundus quadrants following a vitreous hemorrhage.
This study aims at testing the effectiveness of a web-based self-help intervention for people with mild to moderate suicidal thoughts.
A home-based peripheral muscle training program (Five Basic Exercises program (5BX)) is more effective in [a] increasing exercise capacity (e.g. peak work rate) and [b] patients’ preferred occupational performance when it is preconditioned by…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
We expect a decrease in the expected satiating capacity of the test food after repeated exposure to the low-energy-dense version of the soup and an increase in expected satiation after the repeated consumption of the high-energy-dense soup.
6MP treatment in pediatric ALL patients can be improved by developing a pediatric oral drinking solution of 6MP, assessing its bioequivalence, and -when successful- introducing the new formulation nationwide.
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
1. What is the effect of the training program on physical health, depressive symptoms, cognitive and executive functions of people with dementia in comparison with care-as-usual? 2. What is the effect of the training program on physical health,…
The purpose of this study is to develop a brief and child-friendly trauma screening instrument to identify children with PTSD and other trauma related symptoms.
We hypothesize that subjects (Asian or Caucasian) with the COMTH allele (Val/Val polymorphism) respond stronger to the GT treatment than subjects with the COMTL allele (Met/Met polymorphism), consequently have an increased EE and that the genetic…
To assess whether children with relapsed/refractory AML, who do not achieve remission or relapse after treatment with the Relapsed AML 2001/01 standard reinduction protocol (fludarabine, cytarabine and GCSF with or without DaunoXome�), can be…