142 results
The objective of the study is to establish the effect of genestein in patients with MPS III on urinary and serum GAGs levels, hair morphology, GAG accumulation in skinbiopsy, cognitive functions and behavior (Piotrowska et al, 2008).MPS III is a…
Primary Objective:To evaluate the efficacy of OxabactTM to reduce urinary oxalate levels (molar oxalate to creatinine ratio) from Baseline to Week 24 in subjects with Primary Hyperoxaluria (PH).Secondary Objectives- To evaluate the safety of…
Primary objective of this study is: To assess the efficacy of adjuvant therapy of ALD-101 in accelerating platelet engraftment in patients also receiving a standard unrelated UCBT for treatment of inborn errors of metabolismThe secondary objective…
1) To investigate the relative contribution of different neurocognitive dysfunctions toADHD.2) To identify potential baseline EEG/MRI markers of different neurocognitive functions in ADHD children and healthy controls.
The primary aim of this study is to assess the applicability of RT3DE for the evaluation of left ventricular function in daily clinical practice of a pediatric cardiology service.
1) To establish the concurrent validity of the objective Monetary Incentive Delay Task with the BIS/BAS questionnaire as measure of BIS and BAS functioning in healthy children, adolescents, and adults. 2) To get more insight in the development of…
To determine the 1 year sustainability of the effects of a lifestyle intervention on NAFLD in severely obese children and determine the relation between long term changes in liver steatosis and other clinical and biochemical parameters. Finally, to…
The goal of this project is to develop and test a digital file that is expected to improve the communication between professional caregivers (endocrinologists, nurses, dietitians, social workers, psychologists). Additionally, the communication…
The goal of this study is to improve the diagnostic work-up of the small bowel in children suspected of IBD or diagnosed with CD and with suspicion of small bowel disease by comparing enteroscopy as gold standard to ultrasonography, Magnetic…
The purpose of this study is to describe how parents try to help their child in coping with parental cancer. It will be investigated if parental help affects the coping strategy of children to deal with their parent*s illness and subsequently their…
The overall aim of the study is to identify the role of indoor biological and chemical agents that lead to respiratory, inflammatory and allergic health impacts in school aged children. The focus is on microbial exposures due to dampness problems of…
The purpose of this study is to evaluate the quality and effect of scoliosis brace treatment, by means of correlating body brace interface pressure and scoliosis correction in combination with quality of life questionnaires.
European registry of children and patients with congenital heart disease that undergo ICD or CRT implantation. This will lead to a larger amount of data leading to increased knowledge about long-term consequences and potential complications.
Analyze the correlation between change in EELV with change in MIF¬50
The objective of this registry is to obtain long-term safety and clinical statusinformation on pediatric patients with IBD (ie, CD, UC, or IC).
zie protocol
The aim of the Survey is to better understand the variability and progression of Pompe disease and to continue to monitor and evaluate the long-term effects of available treatment options and support measures including ERT with alglucosidase alpha…
The aim of the current study is to identify how increased genetic risk for developing a psychotic disorder affects brain development by studying neurobiological and neuropsychological, clinical an environmental markers in first and second degree…
During the planned follow-up measurements, (T1 and T2), we anticipate that approximately 20% of the cohort will develop schizophrenia. The partition of the sample into *cases* and *controls* with respect to this diagnosis is the basis of all studies…
The main objective of this study is to estimate the rate of response to dasatinib in children and adolescents with certain types of Ph+ leukaemia either whose disease is resistant to, intolerant to or relapsed after previous imatinib therapy or are…