35 results
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
radiological factors for DRUJ instability may account for DRUJ instability in patients after a consolidated distal radius fracture with negative influence on outcome
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
Firstly, we hypothesise that Acceptance and Commitment Therapy (ACT) for diabetes patients will reduce depressive symptoms and will increase diabetes self-care behaviour. Furthermore, we explore the underlying operating mechanisms of ACT. We…
Performing a standard laboratory package prior to the first visit to the outpatient clinic rather than performing laboratory tests afterwards will lead to a shorter time until the diagnosis has been established.
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…
Short-term (1-year) results of renal transplantation are now excellent (over 95%). Long-term (10-year and longer) results are, however, still disappointing. Where most research has focused on immunosuppression and infections, we hypothesize that due…
Deep neuromuscular block has advantages over a moderate neuromuscular block in term of outcome (pain, respiration) but has otherwise no effects on the patient
Early mobilisation, i.e. 6 hours after vascular closure after TF-AVI procedure, will maximize comfort, lower pain complaints, lower infection rate and raise overall patient wellbeing after TAVI-procedure without extreme increase in vascular…
It is safe and feasible to use the Con-Cord table for the ABC approach for stabilisation of preterm infants at birth.
this study will contribute to the implementation of shared decision making in the field of hand therapy, by mapping experiences with the application of shared decision making in current practice and by getting insight information in needs and…
The module “Working with parents in creating a pleasant school” positively effects the attitudes, efforts and self-efficacy of teachers, parents, students in (jointly) counteracting bullying.
We hypothesize that early programming leads to differential brain function. A result of these changes in brain function will be differences in energy expenditure and food intake leading to different eating behaviour and differences in sensitivity to…
Decreased levels of vitamin D is associated with the occurence of peripheral neuropathy in multiple myeloma patients.