271 results
The main objective is to determine the effect of different anticoagulant and procoagulant agents on thrombin generation in whole blood and compare it to the effect on thrombin generation in PPP and PRP at different tissue factor concentrations. In…
The purpose of this study is to determine the thermal parameters by MRI scans at different time points during head-neck radiotherapy combined with hyperthermia treatment series.
The purpose of this study is to demonstrate the effectiveness of renal denervation in lowering blood pressure in patients with therapy-resistant hypertension and end-stage renal disease who are on dialysis or who have a renal transplant.
Primary Objective: To identify variants in the humane genome that are associated with BE risk. Secondary Objective(s): We will collect information on BE length, complication of BE (dysplasia, ulcer, stricture or EAC), presence of esophagitis and…
Evaluation of long-term position, volume and FDG-uptake of the orchidopexied testis because of congenital undescended testis.
Predicting fluid responsiveness during PLR and fluid challenge (FC) by changes in (Pms).
The general aim of this study is to implement validated markers for CAA in asymptomatic individuals with CMBs, to investigate whether presence of CMBs signifies early CAA.
In this proposed study, we aim to test not only the safety and biodistribution of [68Ga]Sarabesin 3, but also its potential to visualise prostate cancer. If the peptide proves to be successful, a next study will be initiated to test the potential to…
Is, when EE is kept constant, replacing sitting time by NEA more effective than exercise in improving glucose control in people with DM2?
The primary objective of this study is to evaluate the effect of multiple oral doses of vemurafenib (960 mg BID) on the PK of a single oral dose of acenocoumarol (4 mg).The secondary objective of this study is to assess the safety and tolerability…
To assess the efficacy, measured as progression free survival, and safety of Selumetinib in combination with docetaxel, compared to docetaxel alone, in patients receiving second line treatment for KRAS mutation negative locally advanced or…
Primary goal: determine the diagnostic quality of CE-MRI scans acquired in supine positionSecundary goal: determine the accuracy of deformable image registration between prone CE-MRI and non-CE-MRI in supine position as an alternative option
The primary goal of this study is to investigate the effect of low doses of mirtazapine and quetiapine on sleep, assessed using polysomnography and subjective sleep measures, of healthy subjects whose sleep will be disturbed by auditory stimuli (…
The aim of this study is to determine whether the presence and the extent of periodontitis are independently related to the presence and extent of coronary calcification.To determine if periodontal treatment has an positive effect on the…
Primary objective:To determine the CT-based femoral component rotation of the *Zimmer Gender-Solutions Patello-Femoral Joint (PFJ) System* relative to the transepicondylar axis; Secondary objective:To relate the CT-based femoral component rotation…
To establish the safety and preliminary efficacy of Check-Cap*s P1 Capsule System in patients eligible for CRC screening
The objectives of this study are to evaluate cardiac performance characteristics and adverse events rates associated with the EDWARDS INTUITY Valve in patients undergoing aortic valve replacement (AVR). The AVR surgical approach is either full or…
Primary aim of the study is to investigate if motivational interviewing can be an effective way to motivate en stimulate patients with recent TIA or ischemic stroke to change their lifestyle and maintain this healthy lifestyle. Moreover we will…
The present study protocol proposes a novel cGMP Enhancing Therapeutic Strategy (cGETS) to 1) enhance plasma levels of cGMP, 2) to increase cGMP-related control of the myocardial response to low dose dobutamine stress testing, 3) to improve…
The primary objective to our study is assessing functional outcome, quality of life, and genetic mutations in patients with a cloacal malformation. Functional outcome:- Colorectal functiono Objective: assessing colorectal function through the use of…