4129 results
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
The primary objective of this study is to analyse the microenvironment of the primary tumour and sentinel and non-sentinel lymph node(s) (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients…
1.1 Overall Aim: To establish a safe, standardized protocol for the perioperative management of patients with atrial fibrillation (AF) who are receiving a novel oral anticoagulant (NOAC) drug, either dabigatran, rivaroxaban or apixaban, and require…
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
Optimise post PVI management using ambulant continuous patient-driven eHealth monitoring after catheter ablation in the treatment of atrial fibrillation.Primary Objective:1) Determine the effect of eHealth on clinical management, outcomes and…
to identify novel molecular pathways resulting in premature atherosclerosis (PAS) in families where the traditional risk factors are not present / near absent.
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
To establish a healthy control group for microcirculatory parameters for current and future studies on the paediatric microcirculation.
A study to explore three different diagnostic tools (predictors) (tcPO2 measurement, BOLD MRI and DCE MRI) quantifying the degree of tissue perfusion and oxygenation at the intended amputation level in patients with refractory critical limb ischemia…
- To compare relative myocardial mass distribution (i.e. mass of the respective territories of LAD, LCX and RCA) by CT scanning to normalized hyperemic blood flow in the three major myocardial territories as assessed by absolute flow measurements…
To compare the level of the sIL-2R between patients who are referred to the Center for Pain Medicine with a suspicion of CRPS but do not fulfill the new IASP Clinical Diagnostic Criteria for CRPS and those who do fulfill the new IASP Clinical…
The aim of this project is to assess the effectiveness of the Untire app in reducing Cancer Related Fatigue (CRF) and improving Quality of Life (QoL) in (former) cancer patients. It further aims to identify the parts of the app that are the…
To determine the within and between variability of pharmacokinetic (PK) profiles in patients treated with DOACs in daily practice
The purpose of Part 1 of the research is to look at the usability and accuracy of the automatically determined CT visualizations and measurements.The purpose of Part 2 of the study is to determine whether the use of the combined information provides…
To study the effect size of FMT after a 3 weeks course of budesonide as induction therapy in patients with active ulcerative colitis despite previous therapy. The purpose of the pre-treatment is to reduce active inflammation prior to donor feces…
The purpose of the current study is to examine the additional diagnostic value of the stress radiograph in determining deltoid ligament disruption in ankle fractures. The sensitivity and specificity of this test will be compared with findings on MRI…
To investigate whether perturbation of the left middle temporal gyrus results in immediate adaptation in the right hemisphere, indexed by a shift of alpha-beta oscillatory effects from the left to the right hemisphere.
To answer the question if dried blood spot (DBS) analysis and saliva hormone testing are reliable methods to determine the concentration of NGF-ß in healthy subjects.
The main purpose of this study is to answer the research question: What is the relation between on the one hand fear of falling and physical activity and on the other hand fear of falling and physical capacity in elderly people from 65 years of age…