341 results
tPA-induced lysis leads to cleaved ADAMTS13: a. accelerating fibrin(ogen) breakdown in in vitro coagulation assays b. leading to impaired platelet adhesion and aggregation in an in vitro flow model
We hypothesize that women who received the one-year three-component lifestyle intervention will have more sustainable changes approximately 5 years after the study with regard to weight, PCOS characteristics, metabolic health, and emotional well-…
New endovascular techniques, such as stents or drug-coated devices, demonstrate superior (patency and limb salvage) outcomes compared to conventional plain old balloon angioplasty (POBA) for critical limb ischemia (CLI) patients based on arterial…
Significantly more patients will express an overall preference for ICI-P versus ICI-B
A blended module for PRT is efficient in improving social communication of children with ASD while increasing accesiblity to the intervention
We expect that participants (young people between 12 and 18 years in a generally healthy population) when asked to exaggerate / feign will show a significantly higher score on Self-report Symptom Inventory's(SRSI) pseudo-symptoms scale than…
the current intraoperative selection of an optimal site for the anastomosis is based on subjective clinical indicators of intestinal viability. As indicated by others there is a need for a gold standard in determining the state of microcirculation…
-Cognitive load will negatively impact taste intensity perception and related brain activation -Cognitive load will not impact hedonic value and related brain activation
We hypothesize that providing persons with information on their personal LIfestyle for BRAin health (LIBRA) profile and access to behavior change support through a smartphone application is feasible.
After surgery for esophageal cancer and gastric cancer micronutrient deficiencies are common and standard suppletion to prevent deficiencies should be performed.
MMC(IRDye800CW)-TOC is safe to inject in patients for intraoperative visualization of gastroenteropancreatic neuroendocrine neoplasms
We hypothesize that flexion induced by uterine contractions can be mimicked by manually performing a knee-to-chest flexion (KCF) leading to spinal flexion directly at birth while the infant is held in dorsoflexion in order to facilitate expulsion of…
The objective of the feasibility pilot is to explore the following questions which will guide proper set-up of the RCT: 1. What is the number of potential participants registered monthly? 2. What is the number of potential participants accepting or…
HSCT recipients are at risk for developing oral complications five years after transplantation.
Testosterone Therapy in (a)symptomatic, testosterone deficient men after Radical Prostatectomy improves functional and oncological outcome compared to testosterone deficient men who do not receive TRT.
The aim of the study is to investigate the effect of magnetic resonance (MR) based online adaptive radiotherapy (RT) for treatment of low to intermediate risk localized prostate carcinoma (PCa) on the radiotherapy dose on the prostate and organs at…
1. To validate the existing guidelines with prospective and retrospective data from this cohort by performing an upper endoscopy at baseline, one year after inclusion and subsequently every three years thereafter in order to assess the risk of…
To characterize the immunological read out, e.g. the immune cell compartments, and antibodies of patients with autoimmune bullous diseases during rituximab treatment and during relapses.
The primary objective is to compare the glucose curve with the OGTT, as a screening test for GDM.The secondary objective is to see if GDM treated after screening either with the glucose curve or with the OGTT, can predict perinatal complications and…
Primary Objectives- To determine the optimal dose of the VEGF-A targeting NIRF tracer bevacizumab-IRDye800CW for an adequate tumor-to-background ratio (TBR) in PTC/FTC/HTC/PDTC lymph node metastases.Secondary Objectives- To evaluate the feasibility…