Search for a trial

Magneto-encephalography (MEG) to image modulation of brain activity by Spinal Cord Stimulation (SCS) treatment in chronic pain patients, an explorative study.

Use Magneto-encephalography (MEG) to image the cortical and thalamic effects that underlie the analgesic effects of SCS for chronic pain patients. To analyse the differences in cortical and thalamic activity between SCS ON and SCS OFF.

Experiences of and Potential Interventions for Stigma according to Personality Disordered outpatients

Primary objectives of study 1:1a. How do Dutch patients with a PD experience stigmatisation by the public and health care providers?1b. How do Dutch patients with a PD experience self-stigma?1c. How can stigmatisation of PDs and its internalisation…

Prospective Longitudinal Cohort Study Children with Vision Impairment

Our aim is to provide the fPRC with empirical data. With studying questions based on literature and practice, the project aims to provide professionals with necessary knowledge to set up early counselling. Besides, the results of the project can…

Clinical Validation of Simultaneous Multi-Slice (SMS) in cardiac MRI

By performing this study, in case the results are positive (SMS images are equally diagnostic as compared to current imaging techniques), the SMS sequence can be implemented in standard clinical care for patients referred for cardiac MRI, reducing…

Study on two new methods for testing visual field in children with brain disease

To compare different methods for visual field testing in young and/or neurologically impaired children, to determine which test is most useful in detecting visual field defects.

Validation of Activity Monitoring system (Activ8) for postures, movements and step detection in hospital patients

The goal of the current study is to determine the validity of an activity monitor (Activ8) for measuring body postures and movements and step count in a hospitalized population.

NutriProfiel applied to athletes - evaluation

Objective: To evaluate the usability (feasibility) of the recently developed tool 'NutriProfiel focused on athletes' so that opportunities can be explored for further improvement and implementation in practice.

Using a drop-in probe to conduct optical measurements during robot assisted laparoscopic prostatectomy

To assess the usability of a drop-in optical probe in terms of quality of optical measurements and impact on current workflow.

Influence of the Menstrual Cycle on the QT interval in females with Long QT-syndrome

Evaluate the effect of the menstrual cycle on QTc among females with LQT1 or LQT2 and to put our previous findings in a broader perspective by including controls groups and older females.

GlucoCEST MRI of the brain in healthy volunteers and patients with brain tumours

To develop a protocol for glucoCEST MRI for brain using the MRI of the recently installed fully integrated PET/MRI apparatus at Erasmus MC.

Intellectual Disability and Epilepsy in Adults: cognitive trajectories and targets for care and interventions

To investigate the trajectories of cognitive and adaptive functioning in adults with epilepsy and ID. In doing so we are looking for clinical determinants of cognitive and adaptive decline. Furthermore, the association between decline and serum…

Monitoring oral mucosal microcirculation in healthy volunteers following oral cooling

The aim of this study is to measure microcirculation density and flow parameters and oxygenation parameters in oral mucosa before and after 30 min of oral cooling with two different cooling methods, in an effort to identify whether oral cooling has…

The haemostatic effect of thawed deep-frozen platelets resuspended in thawed plasma versus room temperature stored platelets in platelet additive solution in the treatment of surgical bleeding; a randomized controlled non-inferiority trial

the primary aim is to determine the effect of thawed deep-frozen platelets re-suspended in thawed deep-frozen plasma versus room temperature stored platelets in platelet additive solution for transfusion on the percentage of patients with surgical…

Incidence and outcome of antibody-mediated rejection in immunological high-risk renal transplantation: An observational PROCARE 2.0 study

To determine 1) the incidence of ABMR and mixed ABMR / T cell-mediated rejection (TCMR) in immunological high-risk kidney transplant recipients treated with the currently prevailing immunosuppressive regimens, 2) to relate ABMR and mixed-type…

Harm reduction in anabolic androgenic steroid use

To investigate:- Whether a harm reduction strategy with education and counseling is effective in reducing the use of AAS by amateur athletes. - The harm reduction potential of an additional online consultation with a well-known fitness expert. -…

Multimodal Optical-imaging of Retinal manifestations of Alzheimer*s Disease

To non-invasively explore the retina for (a) potential biomarker(s) using a multimodal retinal imaging platform (i.a. OCT, OCT-A, ultra-widefield fundus photography and metabolic hyperspectral retinal camera).

A 6-month multicenter, randomized, double-blind, placebo-controlled study to evaluate the
efficacy, safety and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in
addition to an ACEI or ARB, for the treatment of children, 6 months to <18 years of age, with
chronic kidney disease and proteinuria

This study has been transitioned to CTIS with ID 2023-504884-17-00 check the CTIS register for the current data. The main goal of this study is to find out whether finerenone in combination with either an ACE inhibitor or an ARB can reduce the…

The (cost-)effectiveness of a new patient empowered protocol without routine x-rays for follow-up of adolescent idiopathic scoliosis patients; A pragmatic randomized trial

To evaluate the (cost-)effectiveness of a new patient-empowered FU protocol in patients with AIS that is based on patient-reported outcome measures (PROMs), self-assessment tools and physical examination, which is compared to standard or usual FU…

The STELLAR trial: Fluorescence-guided surgery in laryngeal- and hypopharyngeal cancer: a feasibility trial

This study has been transitioned to CTIS with ID 2024-519750-36-00 check the CTIS register for the current data. The primary aim of this study is to determine the feasibility of using intraoperative fluorescence-imaging (FLI) to identify laryngeal…

A pivotal Phase II randomised, multi-centre, open-label study to evaluate the efficacy and safety of MB-CART2019.1 compared to standard of care therapy in participants with relapsed/refractory diffuse large B-cell lymphoma (R-R DLBCL), who are not eligible for high-dose chemotherapy and autologous stem cell transplantation

This study has been transitioned to CTIS with ID 2023-506270-13-00 check the CTIS register for the current data. The primary objective is to determine superiority of MB CART2019.1 treatment compared to standard-of-care (SoC) therapy with R GemOx (…