341 results
The primary objective is to determine the efficacy of the neuroprotectant, nerinetide in:• Reducing global disability in participants with acute ischemic stroke (AIS)
Show that functional MR tumor plasma volume parameters Vp,max and Vp,mean change significantly within 1-6months following start of proton beam radiotherapy of chordoma.
This study will evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of satralizumab compared with placebo in patients with gMG on stable background therapy. In addition, the study will assess the long-term safety and efficacy of…
To study the potential of the daily use of a mini-trampoline or metformin added to the NHG -guided lifestyle to cure early type 2 diabetes in overweight and obese patients. PICO research question. What is the effect of the mini-trampoline or…
To study the feasibility and effects of EMDR on FCR.
The primary objective is to determine the effect of Transvamix on the pain quality item *unpleasantness*, relative to placebo. Secondary objectives include the assessment of general pain qualities, pain self-efficacy, general pain and pruritus…
To investigate whether proton MRI can be used to visualize disease and to study lung mechanics. This new information might give us new insights into the pathophysiology of asthma.
The primary objective of this study is to examine whether the in vitro cellular transfection efficiency of PF14-mRNA nanoparticles is higher in medium supplemented with plasma or serum.
Efficacy: To describe long-term durability of sustained virologic response (SVR) as measured by time to loss of SVR in treatment naïve participants who achieved a complete responseEfficacy: To describe long-term durability of sustained virologic…
Since Triggerfinger and Carpal tunnel syndrome are hand disorders most commonly presented at the outpatient clinic, the aim of our study is to investigate what the effect is of virtual reality use during wide awake local anesthetic tourniquet &…
The primary objective of this study is to validate the accuracy of FebriDx to discriminate between viral and/or bacterial respiratory infections. Besides this, the predictive value (negative predictive value (NPV) and positive predictive value (PPV…
The primary aim of the study is to improve the oral cleanliness of young high caries active children by a HAPA-based intervention to improve the brushing behaviour of parents in their children. Therefore, the effect of the HAPA-based intervention is…
To investigate the prevalence and existence of orofacial abnormalities, in patients with Mucopolysaccharidoses and Mucolipidosis type II and III and how these abnormalities impair the quality of life.
The purpose of this study is to complete the third and final phase of PRO instrumentdevelopment, cross-sectional field-testing of the LIMB-Q. The field-test data will be analyzedto identify the subsets of items for each scale that represent the best…
Objectives: Main objective: A personalized intervention of patients* stress and anxiety based on the combined use of standard measures (e.g. questionnaires) and advanced tools (smart watch sensors, mHealth app and VR) through a radical Artificial…
We aim to investigate in a pilot study the blood platelet mRNA profiles in patients with IIM and a known malignancy.
Our objective is to study SARS-CoV-2 transmission of a- and pre-symptomatic carriers during a mass gathering event with social distancing and hygiene public health measures.Secundary objectives:- To estimate the prevalence of a- and pre-symptomatic…
To determine the pharmacokinetics of CBD and its main metabolites following a single, oral dose of a novel, oil-based hemp extract containing 70 mg CBD, administered to healthy volunteers in fasting and fed condition.
The current research project investigates whether subvocal speech production can be measured using EMGs during AVH. If such subvocal speech is visible in the EMGs, as previous research suggests, this visualization can be used to develop biofeedback…