155 results
The aim of this study is to explore the potential efficacy of IBA as treatment for adolescents with OCD.
Our study objective is to evaluate the efficacy of acetazolamide for the treatment of cystoid macula edema in inherited retinal dystrophies in anticipation of future clinical trials.
Our study objective is to investigate the reliability of commonly used clinical examinations and endpoints performed in patients with inherited retinal dystrophies in anticipation of future clinical trials.
The aim of this project is to examine the association and interaction between environmental and genetic factors and development over time in adults with ASD. We examine if and how genetic and environmental factors might contribute to the course of…
The main objective of this study is to determine the performance of the closed-loop system in adolescents with T1DM. Secondary objectives include: • to assess the safety of the closed-loop system; • to determine the time that the closed-loop…
To examine the determinants of survival of donor RBCs in SCD patientsTo look into the effect of transfusion on the innate immune system of sickle cell patients, in particular, the phenotype of the neutrophils.
Explaining the decision making process surrounding compulsory NF in the view of patients and their parents and their role in it. Also, exploring experiences and the impact of compulsory NF, aiming to identify ways to improve care and provide tools…
With this study, we aim to gain insight in the influence of dietary oxalate on urinary oxalate levels by quantification of the intestinal oxalate absorption in patients with recurrent idiopathic calcium oxalate stones, primary hyperoxaluria, and…
To investigate whether electromyography of the diaphragm during sleep in asthmatic children can be used to objectively monitor asthma control.
Main research question:Does group-based schema therapy result in a reduction of depressive symptoms when comparing symptom change during the treatment to patients* baseline symptom level?Sub research questions:Does group-based schema therapy result…
Objective: The primary objective of this study is to investigate interoceptive abilities in adolescents with AN. To capture the multidimensional perspective, interoceptive abilities will be studied on an accuracy, sensibility and awareness level.…
1. To report the natural history of retinal degenaration in patients with biallelic mutations in the PCDH15 gene.2. To identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in PCDH15-related…
The main objective of this study is to assess the feasibility, acceptability, and effectiveness of four imagery intervention techniques adapted from the protocol of Holmes (2019) for auditory vocal hallucinations. We are primarily interested in…
In this study, we aim to describe cognition and behaviour in patients with DS and analyse correlations between behavioural difficulties and various characteristics including: seizure severity; medication use; level of cognitive functioning; and…
The characterization of the immunophenotypic profile of PBMC subsets in steady state SCD patients. The determination of general T cell function in SCD patients. Both will be used as reference profiles in further research evaluating immune…
The overall aim of the study is to develop innovative minimally invasive monitoring techniques that can identify lung inflammation in pwCF when using highly effective modulators, compared to patients whom are not eligible for CFTR modulators (…
In preparation of a larger intervention study, the aim of the current feasibility study is to test and improve a personalized sport (psychomotor therapeutic) intervention for young people in the first episode of psychosis.
The current study presents a preparational feasibility study. Its aim is to assess feasibility of the GIT-PD Youth intervention on the one hand, and to assess the feasibility of a multicentre research design on the other hand. More specifically, we…
Primary:To estimate the treatment effect of emactuzumab on objective response rate (ORR) by 6 months from initiation of therapy in the blinded phase compared to placeboSecondary:the effect of emactuzumab on clinical outcome assessments (COAs) for:o…
This study has been transitioned to CTIS with ID 2023-507582-25-00 check the CTIS register for the current data. PRIMARY OBJECTIVESThe primary objective of MAKEI V is to assess in a randomized comparison whether the efficacy of Carboplatin (600 mg/…