791 results
The main objectives of this study are:1. The effect of high (2L) vs low (1L) volume bowel preparation on the quality of life of patients undergoing colonoscopy. 2. The cost-effectiveness of low-volume bowel preparation versus high-volume preparation…
To establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve (THV) in subjects with moderate, calcific aortic stenosis (AS)
Primary objective:• To investigate the efficacy, defined as clinical benefit (stable disease (SD), partial response (PR), complete response (CR)) at 12 weeks, confirmed on a second scan after 4 weeks, of an FMT-intervention with responder and non-…
The objectives of the study are:• To understand the phenotypic heterogeneity and phenotype/genotype correlation and natural history of ALSP.• To develop and evaluate biomarkers for assessing disease progression in patients with ALSP.• To create the…
- Confirming the survivorship under normal use of the Collared and Collarless versions of the Avenir Complete* stem (Standard, High Offset, Coxa Vara) and its instrumentation used in primary total, hemi, or revision hip arthroplasty by recording the…
To develop an exergame system which helps patients, ICU staff (including physiotherapists), in ameliorating early mobilisation exercises (frequency, intensity and patient and staff experience), finally aiming to accelerated rehabilitation and reduce…
The aim is to evaluate whether the use of eRFA prior to stenting prolongs stent patency in patients with biliary obstruction due to inoperable perihilar cholangocarcinoma.
To investigate the pain phenotype of patients with hand OA. To investigate the prevalence of neuropathic pain symptoms and central sensitization and their determinants in patients with painful hand OA. To investigate the presence of small- and large…
Main objective:To improve the functional neurological outcome of patients, as measured on the Raschbuilt Overall Disability Scale (RODS) for inflammatory neuropathies (iRODS) with Zanubrutinib in combination with standard treatment with Rituximab or…
Studies of ex vivo muscle cell autophagy flux, leucocyte mitochondrial function and oxylipins, specifically prostaglandin E2 (PGE2) in critically ill patients during admission to an intensive care unit (ICU).
By acquiring functional MR images and brainstem evoked response audiometry (BERA) from the auditory nuclei in the human brainstem, we expect to observe neurofunctional differences between the subjects with unilateral hearing loss, and subjects with…
To assess whether MRI Primovist could replace 99mTc-mebrofenin HBS as a preoperative functional liver assessment in addition to CT-volumetry in predicting PHLF in patients with resectable pCCA who require a major liver resection.
The primary objective of the study is to determine feasibility of CEA assessments at home using (automated) capillary sampling. Home based (automated) capillary sampling will be considered feasible if a success rate of 85% or greater has been…
The aim of this study is to measure eCAPs intraoperatively (and perform electrocochleography [ECochG] in case of any residual hearing) and to estimate cochlear health in these patients by applying insights gained from our guinea pig experiments.
Does isolated cup revision surgery or liner exchange through the anterior approach result in increased functional status and higher patient satisfaction than through the posterolateral approach?
Primary: To evaluate the ability to culture PDEC organoids from pancreatic duct biopsies. Secondary: (i) To evaluate ion transport in PDEC organoids derived from pancreatitis patients. (ii) To evaluate the ability of duodenal organoids to mimic ion…
The aim of this study is to determine the feasibility of perioperative (continuous) remote patient monitoring using Ehealth devices and a daily questionnaire in patients undergoing major gastrointestinal surgery. Additionally, to determine (early)…
To assess the impact of SBRT in combination with systemic therapy compared to systemic therapy alone on safety and efficacy in patients with mCRC.
The objective of this study is to assess the prognostic value of early perfusion changes and infarct evolution detected with magnetic resonance imaging (MRI) acquired directly after EVT.
This study has been transitioned to CTIS with ID 2024-517960-45-00 check the CTIS register for the current data. • To assess the relative change in uptake of [18F]F-AraG in tumor lesions upon anti-PD-1 treatment• To assess the relationships between…