37 results
The primary objective of the current study is to investigate the effectiveness of MCP-ED in a clinical sample of adolescents with an ED. As a result, this study will provide critical information about the potential relevance of implementing MCP-ED…
Implement BBB-ASL at VUmc and assess the reliability and reproducibility of f measurements in healthy volunteers and patients with glioma
We aim to investigate the efficacy of a novel eating disorder prevention program, the Diabetes Body Project, specifically targeting young females T1D. Firstly, we will test the hypothesis that Diabetes Body Project will produce significantly greater…
Main research question and primary objective: What is the effect of exposure to high vs. neutral temperature (32* C vs. 25* C) in combination with high vs. low humidity (30 %RH vs. 70 %RH) for 8 hours on cognitive performance?Secondary research…
Objective: to investigate areas of uncertainty about a possible future definitive RCT using AF-EMDR as an add-on intervention to a Smoking Cessation Program (SCP), by determining:• Feasibility/process outcomes (e.g. recruitment, adherence, treatment…
The aim of the present study is to assess whether the postprandial glucose response of the new test products is superior to the postprandial glucose response of an original treatment option.
As highlighted, significant gaps in knowledge remain regarding etiology of cough, consequences of cough and appropriate treatment of cough in patients with pulmonary fibrosis. A further understanding of the similarities and differences in cough…
Primary objective is to investigate the effect of VR on patient-reported pain outcomes in the ED. Secondary objectives are to investigate the effect of VR on analgesics use, patient-reported outcomes, and process indicators and to identify barriers…
In this study we compare the results of blood sample analysis when blood samples are collected in different tubes from different manufacturers.
Primary Objective- Evaluate longitudinal intra-individual and inter-individual variability of PBMC biomarkers in healthy participants:o LRRK2 protein (pg/mL)o total protein (ug/mL)o pS935 LRRK2/total LRRK2 peptide ratioo pRab10/Rab10 peptide ratio…
The main objectives of the study are to investigate if sleep positional therapy, using the LEFT smartwatch app, reduces nocturnal gastroesophageal reflux symptoms and can train patients to avoid sleeping in right side position.
To examine whether the neutrophil immune profile of healthy geriatric volunteers (age > 70 years) differs from the neutrophil immune profile of young healthy volunteers (age 20 to 25 years).
The primary objective is to investigate the effect of a 3 week intervention with either 1.,3 gram or 2 gram of GOS on the abundance of the genus Bifidobacterium in faecal samples in healthy women of 40 - 70 years old. The secondary objective is to…
To assess the efficacy of the BIHAP (AP® 5, Inreda Diabetic BV) using glucagon and insulin during a three-months period. It is hypothesized that treatment with BIHAP provides better glucose control than current diabetes treatment. Main parameter to…
The primary objective is to assess 2-year survivorship of Total Knee Arthroplasty (TKA) procedures performed using the Smith+Nephew (S+N) Porous Knee System. The secondary objective is to generate safety and performance evidence up to 5 years post-…
In this study we aim to assess the validity of the PriskA algorithm to diagnose PCOS in a pilot study with patients presenting with signs and symptoms of PCOS. The study also aims to collect information on the user experience from the clinicians and…
Primary objective: Identify feasibility of basal-ganglia regions as NF targets in PD patients Secondary objective: Document short-term changes in brain resting-state activation
Primary objective:• To evaluate the safety and tolerability profile of single intravenous doses of AST-004 given as a short loading intravenous infusion followed by a 6-hour continuous intravenous (IV) infusion in healthy adult subjects.Secondary…
To evaluate the effects of an acupuncture treatment protocol for nasal congestion in AR.
• To characterize the systemic response to mucosal immunization with an oral cholera vaccination challenge.• To characterize the local response to intranasal rechallenge after cholera vaccination as outcome measure for nasal mucosal immunity.• To…