101 results
The primary objective of the current study is to investigate whether self-disgust is heightened in patients with AN. If this indeed is the case, this would provide important leads to improve existing treatment options for AN.
This project aims to investigate peripheral and central neuroplasticity following an early (<13 weeks after injury) and intensive (8 weeks of 6 hours of additional therapy) upper extremity motor training program (EIUMT) aimed at recovery…
The aim of this study is to investigate the effectiveness of MST-ID for adolescents with severe behavioural problems from families with an intellectual disability (ID), compared to standard MST. It is hypothesised that MST-ID (n = 150 families) is…
The primary question in this study is: what is the weight development for adolescents with an eating disorder during FBT? The secondary objectives are about the course of eating disorder symptomatology, as well as anxiety and mood complaints. And in…
In the current study, the feasibility, acceptability and effectivity of a new add-on early intervention program for individuals at risk for the development of bipolar disorder is evaluated. This intervention program entails psycho-education, light…
Primary objectives:To evaluate the pathogen host interactions between S. aureus and NS patients:o IgG and IgG4 responses against S. aureus antigens in NS patients will be compared with IgG and IgG4 responses against antigens of other bacteria (e.g.…
To study in two national cohorts of HSCT survivors, treated in different time periods, the prevalence and risk factors of metabolic syndrome, endothelial dysfunction (as a sign of vascular damage) and the clinical phenotypes of accelerated aging so…
The primary aim of the current study is to evaluate the potential effectiveness of online grief-specific CBT, in terms of reductions in symptom-levels of PGD, PTSD, and depression, for children and adolescents who lost a loved one due to a traffic…
Motorized arm support augmenting upper extremity function of people with Duchenne Muscular Dystrophy
The primary objectives of the different substudies are: 1) to identify the level and behavior of passive forces in the arm2) compare different weight and joint impedance compensation strategies of the motorized arm support3) evaluate the overall…
Main objective : To develop a spleen examination dedicated to overweight or obese patients and assessits applicability.Secondary objectives :1. Develop a spleen exam dedicated to patients usually measured with the S+ probe and assess its…
Objective: In this study we propose elucidating the pharmacokinetics of olanzapine in AN patients, to optimize the dosing strategy, to the extent of increasing the efficacy and reducing the risk of side effects. To this end, we will assess the…
(also see: C1. Protocol, page 9, paragraph 2)Primary: Creating a metabolic bio-database with body material of patients with inherited metabolic diseases, combined with clinical data.Secondary: Achieve better participation in national and…
Primary: - Examine longitudinal developmental trajectories of structural and functional brain metrics in relation to genetic, clinical, psychological, environmental, and cognitive information in familial high-risk offspring and control children (…
Primary Objective:Part 1: to characterize platelets of patients with Lowe syndrome using superresolution microscopy.Part 2: to characterize platelet age in patients receiving chemotherapy for AML using artificial intelligence techniques.Secondary…
The aim of this randomized controlled trial is to assess the effectiveness of a guided e-health sleep and biological clock intervention on sleep, mental health symptoms (depression and anxiety), functioning, and quality of life in university…
This study has been transitioned to CTIS with ID 2022-501869-41-00 check the CTIS register for the current data. PrimaryPhase I: To assess the safety and tolerability of the investigational agents and define the MTD/RP2D(s)Phase II: To evaluate the…
The specific aim of the current study is to investigate the impact of oncological treatment and multiple GA in Rb survivors and Rb risk carriers (8-35 years) on cognitive functioning, psychosocial functioning and HRQoL. Furthermore, psychological…
Primary:Evaluate the impact of SoC anemia management on Hgb concentrationsSecondary:- Characterize the use of ESA therapies in management of anemia associated with moderate to severe CKD in children and adolescents aged <18 years- Evaluate…
This study evaluates the efficacy and applicability of schema therapy for anorexia nervosa.
To assess the effectiveness of a cerclage in women with a twin pregnancy with a midpregnancy short cervix compared to standard treatment (no cerclage) in the prevention of extreme preterm birth (PTB) < 28 weeks of GA.