225 results
This research aims to determine factors involved in subfertility and serious pregnancy complications that arise early in pregnancy. Due to increased insight into the pathogenesis of these conditions, primary prevention should ultimately be possible.
Maternal and neonatal vitamin D level play a role on dental development in childhood
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
Knee OA is characterized by the presence of crepitus (knee sounds). Therefore, this device is able to record these sounds, while the subject is doing a knee movement, and screen for the presence or absence of osteoarthritis.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
radiological factors for DRUJ instability may account for DRUJ instability in patients after a consolidated distal radius fracture with negative influence on outcome
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
1. The primary objective of this study is to investigate whether nocebo effects on cowhage-evoked itch can be induced by verbal suggestion. We hypothesize that the verbal suggestion that the solution applied is an ‘itch solution’ will induce higher…
It will be investigated whether passive leg raising and stroke volume variations can be used in predicting renal responses to fluid administration. Our hypothesis is that dynamic predictors of cardiac fluid responsiveness can predict an increase in…
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
Youth at intermediate vocational education (ROC's) show excessive alcohol and drug use, which can have various detrimental consequences. For this vulnerable group of youngsters a targeted, multicomponent plan of attack was developed in…
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
To determine the feasibility of a home based rehabilitation program delivered by means of a tablet-pc for patients after THA To get a first impression of the clinical effectiveness of the rehabilitation program
EN - Unrelieved chronic pain represents a major problem for individual patients and is also a socio-economic burden for health services and the community at large. Although the etiology of musculoskeletal chronic pain following trauma is not well…
The purpose of this study is: 1. To investigate the differential effectiveness of group and individual parent training in PRT on opportunities created by parents and social initiations of children with Autism Spectrum Disorder (ASD). 2. To…