4987 results
Part 1: The primary objective is to investigate if the RNFL-ac in PD patients differs significantly from the RNFL-ac in healthy controls.Secondary Objectives are:1) to investigate if the RNFL-ac can be used to differentiate PD patients from healthy…
The primary objective is to investigate cerebral perfusion in rest and in response to moderate exercise (handgripping or light cycling) and a visual stimulus in patients with severe aortic valve stenosis prior and after surgical or transcatheter…
This study is aimed at two objectives: Objective 1: Development of new clinical fMRI protocols, based on existing cognitive tasks, that provide robust and reliable activation patterns, as well as performance measures that correlate woth…
Frequency of PNH in a selection of patients with DVT. In several publications PNH has been described especially in patients with DVT and younger than 30 years of age and/or with DVT on unusual places.
To visualize the different components of RAP lesions with high resolution Doppler OCT, and to evaluate the change in intra- and transretinal flow after treatment.
The objective of the study is to assess the additional value of monitoring segmental liver function with HBS in patients undergoing SIRT.
1. Esophageal ultrasound guided (EUS-B) sampling of intrathoracic lymph nodes has a14% higher granuloma detection rate compared to endobronchial ultrasound (EBUS)guided nodal sampling in patients with suspected sarcoidosis stage I/II.2. 25G ProCore…
1. To assess the incidence of pulmonary infiltrates by means of low dose CT-scan in patients with a high clinical suspicion of CAP but with a normal chest x-ray 2. The levels of biomarkers (CRP, PCT, White blood cell count) will be compared to the…
Primary objective: to assess the UCP-LF CAA test in travellers with high-risk water contact as compared to routine diagnostics
Facilitation of translation of MR protocols from research to clinical setting.
To test the hypothesis that salivary pepsin is able to predict outcome of treatment in GERD suspected infants.
To evaluate interlesional and intralesional differences in [11C]erlotinib uptake in EGFR mutated (EGFR+) NSCLC patients who are at different stages in their TKI treatment. To correlate tumor [11C]erlotinib uptake to EGFR mutational status, tumor…
Calibration of the mitochondrial oxygen tension technique in the human skin
The aim of this pilot-study is to examine the accuracy of MRL compared to current nodal staging methods. We expect anacceptable accuracy of the MRL based on earlier studies with gadofosveset enhanced MRI in rectum cancer patients. Then the MRL could…
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
Primary objective of this study is to assess changes in brain connectivity and activity in the Default Mode and Salience Network (hypothalamus, prefrontal cortex, nucleus accumbens, Ventral Tegmental Area) after different sugars and sweeteners.
For head and neck (H&N), lung and esophageal cancer, an initial simple screening test would involve interrogation of the buccal mucosa. There are several tissue alterations related to field carcinogenesis that are currently undetectable but…
Goal of our study is to compare the CO measuments by the Oesophageal Doppler Monitor (ODM, Cardio Q) with the TPTD technique (PiCCO) and to determine reliability of the ODM in absolute CO values and as a trend monitor. A validation study comparing…
Primary objective:1. To evaluate the frequency of invasive fungal infections in a prospective pediatric oncology cohort and to identify the determinants of such invasive infections.2. Clinical validation of novel innovative diagnostic methods for…
To evaluate the role of white blood cell (WBC) scintigraphy in monitoring the response of infection treatment of a prosthetic joint infection.