1335 results
To assess the additional prognostic value of combined CTP and CTA parameters to baseline patient criteria and plain CT. Secondary objective is to subsequently use the best CTP and CTA indicators of outcome of infarct in a prediction model for…
Treatment of endometrial hyperplasia by an IUD that contains progesteron is more effective and has less side-effects than the treatment with progesteron oral.
To study the influence of physical inactivity, induced by leg immobilization, on muscle charateristics, satellite cell content and muscle protein synthesis rate.
The aim of the current study is to determine whether long-term follow-up in primary care, under the condition of initial optimization of pharmacological and non-pharmacological treatment at the specialized HF clinic is equally effective as long term…
To study the relationship between (a) abnormal concentrations of plasma amino-acids, pterins, HVA and inflammatory parameters and (b) the severity, duration and outcome of delirium. To find a biochemical profile that predicts the occurrence of a…
1) Study the chemopreventive potential of 5-ASA and UDCA in UC by evaluating the effect of treatment on ACF number, size and rate of dysplasia, relative to the placebo group. 2) Gain mechanistic insight into the chemopreventive properties of 5-ASA…
The aim of this randomized controlled trial is to determine the affect of screening on the Gastrointestinal symptoms (GIS) and Health Related Quality of Life (HRQL) in asymptomatic first degree relatives of CD patients. On the basis of the results,…
To compare the value of HPV transcript analysis and analysis of DNA methylation status with that of cytology examination as tools for stratification of hr-HPV positive women for risk of high-grade CIN lesions and cervical carcinoma (*CIN2). The aim…
This is an exploratory study, consisting of two parts. In part I a dose escalation is performed and the primary objective is the safety of different doses of TLR-DC. In part II TLR-DC vaccination will be compared with cytokine-matured DC vaccination…
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To study the long term safety (up to 5 years) of denosumab in subjects undergoing androgen-deprivation therapy for non-metastatic prostate cancer.
The current proposal aims at testing an innovative, implementable, effective intervention strategy towards stopping of passive smoke exposure in children at risk for asthma.
1. Does mPAT directly impair vasoreactivity to insulin and acetylcholine ex vivo in arterioles obtained from muscle biopsy in lean and obese individuals?2. Is obesity in humans associated with the accumulation of mPAT and an inflammatory mPAT…
- To assess, in a randomized study the value of Azacitidine as post remission therapy (in comparison to observation) in elderly patients with AML, RAEB or RAEB-t with respect to the disease free survival.- In addition, post remission Azacitidine…
The primary objective is to determine the effect on progression-free survival (PFS) of adding MORAb-009 to the combination of pemetrexed and cisplatin in the treatment of subjects with unresectable malignant pleural mesothelioma (MPM). (Protocol ch…
The primary objective is to determine if disease associated lesions in patients with VHLD can be visualized with 89Zr-bevacizumab PET scans. Secondary objectives are to explore if 89Zr-bevacizumab PET imaging can differentiate progressive from non-…
The general objective is to validate and assess the clinical and economic added-value of a) innovative diagnostic tests developed in WP1 (PET tracers), WP2 (ultra high field MRI) and WP3 (CSF), and b) other emerging diagnostic tests for Alzheimer…
To determine the value of a post coital test in the basic fertility work up in WHO class II subfertile women ovulatory after clomiphene citrate (CC).
To determine the composition of immune cells and the expression of immunological factors in normal squamous esophagus, RE, BE and EAC.
The objective of this study is threefold. The first objective of the study is to determine the course of pervasive developmental disorders (more specific PDD-NOS) and thought problems (more specific MCDD). Secondly, possible processes underlying…