1335 results
PrimaryDemonstration of superior efficacy (as measured by PFS time) of L-BLP25 in combination with hormonal treatment (HT) over placebo plus HT, when used for first-line therapy of hormone receptor-positive (ER+ and/or PgR+), inoperable locally…
Investigate the effect of the Etomidatelevel on the seizure-quality of a seizure caused bij electroconvulsive therapy
If proven (cost)effective, without inducing antivral resistance, oseltamivir could have considerable benefits in this setting, although constraints relating to implementation need to be addressed as well. If not (cost)effective if this fragile…
The objective of this study is to show that the results of PTNS are based on the treatment of electrical stimulation and not on a placebo effect with a sham treatment.
Primary: To explore the effect of the H1-antagonist hydroxyzine 50 mg on motor response, attention and impulsivity, using a test battery and task manipulations. Secondary: To explore the effect of the H1-antagonist hydroxyzine 50 mg on…
To investigate the influence of left and right lateral position on the onset of TLESRs and GER and the underlying mechanisms during and after a test meal in GERD patients compared to healthy controls.
A low frequency of defecation (constipation) is a common complaint affecting a large part of the population. Children, adults and elderly can experience chronic inconvenience because of this complaint. Inulin is not digested in the human…
To assess the prevalence of HIV, hepatitis C and B, and (related) risk behavior among hard drug users in care at Mondriaan carecentre for addiction in Heerlen.
The present study aims at testing whether the 0.07% CPC-mouthrinse has a potential to inhibit gingival inflammation as compared to a placebo over a 6 month period.
The objective is to assess the effect of adalimumab on selfconfidence and sexuality of patients with anogenital psoriasis.
Primary objective* To evaluate ocular and non-ocular adverse events during the 24-months study period in patients treated with Lucentis (0.5 mg)Secondary objectives* To describe the ocular and non-ocular adverse events over a cumulative 36-months…
The objective of the study is to standardize portal placement in endoscopic calcaneoplasty, thereby taken into account the three different foot shapes, cavus, valgus and normal feet. Primarily the FOPP- device needs to be validated. If found valid,…
In the present study we want to show that automatic processing of eye-gaze is impaired in autism, and that this deficit influences the way autistic individuals perceive the world. We will test this hypothesis using a masked priming procedure to…
The main objective is to find the neural correlates of route choice with an event-related fMRI experiment.
To sess the relationship between cerebral perfusion and clinical findings (neurological and neuropsychological) in patients with sickle cell disease.To compare iamging fincdings in children with and without sickle cell disease.
To investigate if a dosage advice for darbepoetin and iron generated by a pharmacist leads to an increase of haemodialysis patients whose haemoglobin values lie within the target range, compared to dosage of darbepoetin by the nephrologist alone.
To investigate whether a one year Taekwondo training one hour a week improves dynamic locomotion aspects and balance parameters in middle-aged, healthy persons. Cardio-respiratory function and static movement components will also be measured.
The present study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of ARA 290 administered intravenously to patients with ESRD.
To gain information about the characteristics of the oVEMP response in patients with BRIC type 1
To study potential abnormal functioning of the bile salt-FXR-FGF19 axis in patients with clinically quiescent Crohn*s colitis.