4231 results
The literature indicates that a minimal endoxifen concentration of 16 nmol/L is needed to produce a therapeutic effect. This implies that the endoxifen levels in individual patients must stay above this threshold throughout the entire treatment…
This study will test the effectiveness of Dragon in improving ADHD related symptoms, specifically in the areas of selective attention, impulsivity, hyperactivity/motor inhibition and motor skills in children with elevated ADHD-symptoms. It is…
Poor glycaemic control, indicated by an elevated HbA1c, is correlated to poor postoperative outcome in patients with diabetes mellitus undergoing surgery. However, improving glycaemic control before surgery has not been extensively studied so far.…
If there is a correlation between liking by smelling and liking by vaping, future experiments on e-liquid flavors would require smelling experiments only.
We hypothesize that receiving behavioural triggers, sent as text-messages via a smartphone app, results in increased diabetes self-management of type 2 diabetes patients on insulin therapy, and subsequently to improved glycaemic control, less weight…
The aim of the NEtherlands Chlamydia Cohort STudy (NECCST) is to assess the risk of developing complications and the time to pregnancy in women with and without a known previous Chlamydia trachomatis (Ct) infection. Furthermore, this study aims at…
The hypothesis is that a combination of exercise therapy and splinting is superior to splinting alone in the treatment of patients with thumb base osteoarthritis.
The hypothesis is that the 'Shine!' intervention will result in parents having better parenting skills and a higher self-efficacy to twice daily brush their children’s teeth, resulting in better oral hygiene and less dental caries…
The invasive bacteria Shigella and entero-invasive E.coli (EIEC) that cause gastro-enteritis, are genetically related and share an infection mechanism. In the Netherlands, Shigellosis is a notifiable disease, while infections with EIEC are not. With…
Children with underlying medical conditions, prematurity and low birth weight are at increased risk of hospitalizations due to rotavirus (RV) gastroenteritis, RV related complications and mortality. In a recent Dutch study it was demonstrated that…
Sentinel node mapping for bladder cancer is possible using the hybrid tracer ICG-99mTc-nanocolloid
Prosody, both linguistic and emotional, is essential in the acquisition and usage of language and socio-emotional development, but it proves difficult for CI users because of their relative inability to hear spectral and, to a lesser degree, dynamic…
We expect maternal hyperoxygenation in the presence of fetal distress during labor to reduce abnormalities in the fetal heart rate tracing and to reduce the need for assisted birth or a emergency caesarean section without severe maternal or fetal…
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
This study is designed to evaluate the effectiveness and safety of the ApiFix (MID-C) System.
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
Fatigue is expected to be the most prevalent symptom in patients with ILD (IPF and sarcoidosis), next to dyspnoea. Frequency of moderate to severe fatigue in patients with ILD is unknown. In addition, possible correlates of fatigue, including age,…
The purpose of the study is to investigate whether we can ameliorate (associative) learning processes in children with ADHD by training working memory. We predict that children in the active working memory training condition will show improved…
Children participating in daily sport classes will attain higher academic achievement than their counterparts who participated in the standard physical education classes incorporated in the school curriculum (1 hour/week).
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training