1376 results
This is an exploratory validation study in a small group of subjects receiving a CI to verify if ECoG measurements with AB*s novel ECoG system are useful as an intra-operative tool for soft surgical techniques to spare residual hearing. This trial…
To determine whether DUX4 can be detected in epithelial or stem cells isolated from midstream urine and/or buccal brush biopsies and/or skin punch biopsies of FSHD patients. Hereby we will assess whether any of these biomaterials can be used as an…
Thermoregulation in patients with spinal cord injury and cold sensations, an explorative pilot-study
To investigate whether SCI patients with regular complaints of cold sensations in daily life have more impaired thermoregulatory responses to changes in environmental temperature compared to SCI patients who do not have these cold sensations in…
Evaluate whether CT lung densitometry and PWV associate with plasma DES concentrations. In addition, we want to determine whether certain other laboratory determinations in the blood and condensed exhalation vapor correlate with plasma DES.
The primary objective of this study is to investigate if shear-wave elastography and contrast-enhanced ultrasonography can identify those patients most suitable fir an intervention (surgery or endoscopic balloon dilation) and those patients that…
Objective: The primary objective is to analyse whether LSCI could be integrated in a PAOD endovascular operation program in a HOT, for the visualisation of the microcirculation of the foot. Therefore, stability and reproducibility of the system,…
In this study we want to investigate how a perturbation-based treadmill training with cognitive dual-task improves daily life gait stability in older adults compared to conventional treadmill training with cognitive dual-task.The results of this…
To assess the presence of absence of ILCs in preclinical (early) pSS biopsies as well as to assess their potential interaction with epithelial cells.
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
The primary aim is to assess myocardial development and function of the left ventricle in fetuses with the suspicion of aortic coarctation on fetal echocardiography. The secondary aim is to study left ventricular blood flow movement with vector…
Taken together, social performance monitoring processes and empathic abilities are key ingredients for efficient social behavior. Possible disturbances in these processes may severely inhibit or even impair social interactions with possible long-…
To assess the variability of semi-automated volume measurements of pulmonary nodules in patients with known or suspected pulmonary metastases on same-day repeated scans of equal radiation dose from two different CT scanners: CT scanner with standard…
To determine the efficacy of a filter-based depletion of RBC-pathogen complexes by a single apheresis tretatment in patients with sepsis.
To investigate if a personalized dietary advice is more effective in increasing dietary fiber intake in the Dutch population than the general advice that is currently provided by the Netherlands Nutrition center and the Dutch Digestive Foundation (…
The primary objective of this study is to describe the long-term safety of dupilumab in the treatment of patients with moderate to severe asthma who completed the previous asthma clinical trial, TRAVERSE-LTS12551.
To compare the immunobiology of healthy volunteers to (advanced) cancer patients to age-matched controls with no history of cancer and no potentially interfering medication.
Victims of IPV, living in an unsafe and unhealthy situation, are faced with a broad range of physical and emotional symptoms. Standard and easy-accessible care to facilitate change into a safer situation is lacking. The project aims to launch an…
Investigate anatomy, kinematics, clinical outcomes, and functional outcomes in Madelung deformity patients.In this study we will answer the following 3 questions:1) What is the anatomical situation of the wrist in patients with Madelung deformity,…
Primary objectiveThe primary objective is to assess the organizational and financial feasibility of implementation of the DLAM-treatment programme for T2D patients in primary care. This includes an observational cost-benefit analysis, informing…
To analyse long-term structural joint changes after knee joint distraction as a treatment for knee osteoarthritis by use of radiographs