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LSD microdosing - A repeated dosing study

The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…

Single tooth implants in the posterior maxilla and mandible: a prospective study on clinical performance of Atlantis CustomBase solution with full-contour zirconia Atlantis Crowns.

Good clinical performance compared to literature

ROTEM in critically ill patients at risk for DIC

ROTEM is able to detect DIC and predict which patients are at risk of bleeding or thrombosis. Furthermore, we hypothesize thromboembolic events due to DIC occur when fibrinogen drops below a certain value compared to DAMP levels.

Third evaluation of the National Patient Safety Program in Dutch hospitals: A Safety-II approach using FRAM analysis

By using FRAM, healthcare professionals will gain more insight into the variability of the healthcare processes, which leads to improved compliance with the selected safety indicators.

Feasibility and potential effectiveness of the primary care functioning scale in daily general practice

In this pilot cluster randomized control trial, primary care practices will be randomized either into the professional-guided PCFS group (in which patients will be seen by the practice nurse during their regular scheduled consultation follow up of…

Evaluation of the relationship between AGEs and treatment outcome of vitrectomy in PDR patients

skin autofluorescence is a predictor of treatment responsiveness in patients who underwent vitrectomy because of PDR

The use of post-ERCP pancreatitis prophylaxis and recognition of risk factors for post-ERCP pancreatitis among Dutch gastroenterologists: a nationwide practice survey

We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…

Personalised combined lifestyle intervention

1. Personalised tools and technologies help to stimulate an increased compliance to a healthy lifestyle in people with overweight and/or obesity and who are cardio-metabolically compromised. Increased compliance may (eventually) lead to a more…

The effects of quark ingestion with or without prior exercise on muscle protein synthesis rates in young and older men.

We hypothesize that the ingestion of quark will increase post-prandial muscle protein synthesis at rest in both young and older men. In addition, we hypothesize that exercise will augment the post-prandial muscle protein synthetic response to quark…

Hypersensitivity in eosinophilic esophagitis

We would further elucidate the presence of hypersensitivity in EoE and its relation to the esophageal mucosal integrity

Potential screening participants’ and physicians’ preferences on optimizations of population based colorectal cancer screening, a discrete choice experiment

Individuals have preferences towards certain attributes of CRC screening optimizations

Effectiveness of response restriction with prompting combined with overlearning in children and adolescents with day-time urinary incontinence/non-retentive faecal incontinence.

RR with prompting results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents. The addition of overlearning will result in better maintenance of the acquired skills over time.

CSI as a marker for active EoE

Our hypothesis is that contratile segment impedance is a marker for EoE-disease activity (histological remission or active disease)

PRospective Observational cohort Study of reached Protein and Energy Targets in general wards during the post intensive care period-I

In the post-ICU hospitalization, the nutritional intake of post-ICU patients is below targets (based on predicted requirements)