3434 results
The primary aim of this study is to accurately compare the mid and long-term migration of two uncemented total knee prostheses. The secondary objectives of this study are to evaluate whether inducible displacement can be used as a parameter to…
We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.
This proof-of-concept study aims to prove the safety and usability of OCT in BTK lesions. Furthermore, it aims to provide information on the discrepancy between objective measurement of the vessel diameter using OCT versus the estimated vessel…
Main Objective:To evaluate the efficacy of REN001 in subjects with PMM treated for 24 weeks, assessed by the effect on exercise endurance.Secondary Objective:To evaluate the efficacy of REN001 in subjects with PMM treated for 24 weeks, assessed by…
Research question: Is maternal microbiome dysbiosis in MOB an underlying mechanism in the pathophysiology of adverse maternal pregnancy and offspring outcome?Objectives: Analyse the differences between the gut and vaginal microbiome, maternal and…
To investigate the short-term effect of a vegan diet on daily muscle fractional synthesis rates in comparison to an omnivorous diet in community-dwelling older adults.
To explore the feasibility and opportunities for new imaging procedures, of relevance of Amsterdam UMC prioritized areas, that a ultra-high sensitivity total body PET-CT system can offer for improving diagnosis and dose reduction.The protocol…
This study has been transitioned to CTIS with ID 2023-505405-17-00 check the CTIS register for the current data. The main objective of this Phase IIa/b study is to demonstrate the effectof zibotentan on HVPG, and that dapagliflozin can mitigate…
Objective: Evaluate uterine contraction features (frequency, amplitude, direction, and coordination) using a dedicated speckle-tracking algorithm by 2D transvaginal ultrasound measurement in postmenopausal women presenting with vaginal bleeding or…
The main objective of the proposed study is to investigate the effect of a VLCKD on body composition in patients undergoing bariatric surgery, and to compare this with a standard VLCD.
The primary objective is to examine relationships between neurocognitive performance and MRI parameters of brain vasculature, metabolism, and white matter diffusion in children who have been treated for posterior fossa tumor. Secondary objectives…
The main objective of this study is to investigate whether rTMS treatment will improve clinical outcomes in body dysmorphic disorder, by reducing BDD YBOCS outcomes. Furthermore to improve localization and rTMS treatment in the dorsolateral…
This study has three specific objectives:1) to explore how the participants* intercorporal bone grafts HU develop over time in the first two years after fusion surgery.2) to explore the interobserver reliability of the HU measurements.3) to explore…
Primary Objective: - To establish the population range (24-h AUC) of high-dose infusional 5-FU in patients with locally advanced, resectable gastric or gastro-esophageal junction cancer treated with perioperative FLOT.Secondary objectives: - To…
1. Primary objectiveThe primary objective of this clinical investigation is to evaluate implant survival rate 1 year afterpermanent restoration (PR), i.e. implant in place 1 year after PR, Yes/No.2. Secondary objectivesThe secondary objectives are…
Through the utilization of fMRI and DUS we aim to illustrate the physiological change a kidney graft undergoes during a transplantation trajectory from donor to recipient. Secondarily, we intend to establish a baseline reference for normal…
To study the direct effects of long-term intermittent fasting on immune cell populations in the blood, combined with analyses of systemic metabolic fitness and inflammatory activation of leukocytes.
The purpose of the current study is to test the effectiveness of both trainings (IBT and ABT) in a non-clinical and clinical sample, with the future goal of making the training available to all patients with BPS. The central objectives for this…
This study has been transitioned to CTIS with ID 2023-505836-36-00 check the CTIS register for the current data. Main Objective:To demonstrate the superiority of galcanezumab versus placebo in the prevention of migraine in (at least) 1 of the…
Lifestyle intervention programs reduce inflammatory activity and might, therefore, be of added value in the management of patients with an inflammatory arthritis. Therefore, the aims of this randomized controlled trial are: 1. To compare the…