3434 results
The primary objectives are:* United States Food and Drug Administration (FDA) primary objectiveTo demonstrate noninferiority in subjects who received an allogeneic BMT for subjects randomized to Rezafungin for Injection compared to subjects…
Primary objectives:• to assess the safety of combining nivolumab, ipilimumab and up to 3 fractions of medium dose hypofractionated radiotherapy (mRT) to multiple tumor sites (1 to 4, with at least 1 site receiving 24Gy)• to explore the efficacy of…
The primary objective is to evaluate long-term reperfusion rate, neurological outcome and quality of life in patients with unruptured intracranial aneurysm treated with the Surpass Flow Diverter (Surpass; Stryker Neurovascular, Fremont, CA).
We aim to investigate the renal hemodynamic effects of empagliflozin in people with either preserved or impaired renal function with T2DM and people with impaired renal function without T2DM, all with and without adenosine blockade.
The primary objective of this study is to investigate the effect of a six-week period personalized food intervention with prebiotic supplementation on intense exercise performance in healthy, recreationally active adults. Further, this study has…
The main objective of the present study is to compare the clinical outcome of bone marrow stimulation alone versus bone marrow stimulation and bone marrow aspirate concentrate (BMAC) for small symptomatic osteochondral defects of the talus.
To determine the clinical value of ultrasound, in addition to other non-invasive parameters of disease activity in children aged 3-18 with Crohn*s Disease.
This study has been transitioned to CTIS with ID 2024-512968-57-00 check the CTIS register for the current data. The primary objective of the study is to assess the safety and feasibility of autologous salivary gland stem cell transplantation of the…
The main objective is to determine the accuracy of the Guardian Sensor 3 in combination with the transmitter developed by Inreda Diabetic BV. Secondary objectives are to assess differences in sensor performance parameters between the Guardian Sensor…
To investigate the effect of bisphosphonates and the MMR vaccine on BCG-induced trained immunity as a possible preventive approach against COVID-19
1. To compare the proinflammatory, profibrotic and osteogenic cytokine profile in BAL fluid between SSc patients without ILD, with limited ILD, and with extensive ILD.2. To compare the proinflammatory, profibrotic and osteogenic differentiation of…
The primary objectives are to demonstrate the safety and performance of the Exthera Medical Seraph 100 Microbind Affinity Blood Filter in the reduction of pathogen load from the blood in septic patients with suspected, life-threatening bloodstream…
The main objective is to compare range of motion between a mobile bearing posterior stabilized knee device and its non-stabilized mobile bearing counterpart. Secondary objective is to compare patient reported outcome measures (PROMs) between both…
The aim of this study is to prospectively assess the benefits and effectiveness of non-complex gallstone clearancefluoroscopy / radiation-free direct solitary cholangioscopy (DSC) comparing the SpyGlass * system to non-complex biliary stone…
To deliver:data to be used as part of a reference database for the EUROBENCH-framework.To assess:- to what extent transfemoral and transtibial amputees are able to adapt to standing and walking on slopes and laterally inclined surfaces in terms of…
To determine the presence and predictive value of MLE on cognition after DBS in PD.
The objective of this study is to assess the effect of galacto-oligosaccharides (Biotis* GOS Omni powder) on the number of bowel movements in an adult population with self-reported constipation.
Primary objectives: 1. To develop a prospective cohort in the Netherlands of chronic HIV infected patients with in-depth reservoir characterization for future cure interventions.2. To study the evolution of the HIV reservoir and immune host…
1. To investigate the efficacy of dual therapy (omitting acetylsalicylic acid) compared to triple therapy in patients with atrial fibrillation and acute coronary syndrome.2. To investigate the safety of dual therapy (omitting acetylsalicylic acid)…
The primary objective of this study is to develop a method by which large numbers of immune cells can eventually be obtained from a kidney biopsy to study phenotype and function of immune cells and unravel mechanisms contributing to loss of renal…